Table 3.

Toxicity Associated With CD4+ DLI

Dose Level (CD4+ cells/kg)GVHD Neutropenia (ANC <500)Thrombocytopenia (Plt <20,000)
Acute ChronicAcute + Chronic
1 (0.3 × 108)  4/27  2/27  4/22  3/22  
2 (1.0 × 108) 1/5  1/5   1/5  0/4 
3 (1.5 × 108)  1/6  2/6  1/6  2/6 3/6  
Total  6/38  3/38  3/38  7/33  6/32 
Dose Level (CD4+ cells/kg)GVHD Neutropenia (ANC <500)Thrombocytopenia (Plt <20,000)
Acute ChronicAcute + Chronic
1 (0.3 × 108)  4/27  2/27  4/22  3/22  
2 (1.0 × 108) 1/5  1/5   1/5  0/4 
3 (1.5 × 108)  1/6  2/6  1/6  2/6 3/6  
Total  6/38  3/38  3/38  7/33  6/32 
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