Characteristics of Infused Cells After Ex Vivo CD8 Depletion
| Dose Level . | N . | Median No. of Pheresis Sessions/Patient . | CD3 . | CD4 . | CD8 . | CD56 . | CD20 . |
|---|---|---|---|---|---|---|---|
| 1 | 28 | 1 | 3.5 (2.1-3.0) | 3.0 (2.1-3.7) | <0.01 (0-0.2) | 0.3 (0-0.9) | 0.4 (0.1-0.7) |
| 2 | 5 | 2 | 11.3 (8.1-13.1) | 9.4 (7.9-10.3) | <0.01 (0-0.1) | 1.0 (0.4-1.9) | 0.9 (0.2-2.4) |
| 3 | 7 | 2 | 13.2 (10.4-18.8) | 13.2 (10.9-16.8) | <0.01 (0-0.1) | 2.3 (1.4-6.4) | 1.6 (0.7-2.7) |
| Dose Level . | N . | Median No. of Pheresis Sessions/Patient . | CD3 . | CD4 . | CD8 . | CD56 . | CD20 . |
|---|---|---|---|---|---|---|---|
| 1 | 28 | 1 | 3.5 (2.1-3.0) | 3.0 (2.1-3.7) | <0.01 (0-0.2) | 0.3 (0-0.9) | 0.4 (0.1-0.7) |
| 2 | 5 | 2 | 11.3 (8.1-13.1) | 9.4 (7.9-10.3) | <0.01 (0-0.1) | 1.0 (0.4-1.9) | 0.9 (0.2-2.4) |
| 3 | 7 | 2 | 13.2 (10.4-18.8) | 13.2 (10.9-16.8) | <0.01 (0-0.1) | 2.3 (1.4-6.4) | 1.6 (0.7-2.7) |
Values are the number of cells infused per patient × 107 cells/kg given as median (range in parentheses).