Lymphocyte Profile Before and After Bone Marrow Transplantation
| Parameter . | Pretransplantation . | Months Posttransplantation . | ||||
|---|---|---|---|---|---|---|
| . | . | 1 . | 2 . | 3 . | 4 . | 5 . |
| Lymphocytes (per μL) | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 3,658 | ND | ND | 4,154 | ND | 3,962 |
| 734 | ND | ND | 10,492 | ND | 12,366 | |
| 1,062 | 1,050 | 8,624 | 8,786 | 7,708 | 7,100 | |
| 874 | 986 | 8,316 | 4,251 | 4,408 | 4,464 | |
| Phenotype (%) | ||||||
| B | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 17.5 | ND | ND | 8.1 | ND | 11.2 |
| 46.5 | ND | ND | 1.8 | ND | 4.1 | |
| 83.7 | 37.5 | 4.7 | 3.5 | 5.5 | 6.3 | |
| 42.8 | 40.8 | 3.7 | 6.8 | 5.2 | 7.1 | |
| CD3 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 54.6 | ND | ND | 76.1 | ND | 78.7 |
| 3.4 | ND | ND | 89.9 | ND | 90.6 | |
| 0 | 36.8 | 91.8 | 90.4 | 83.9 | 92.2 | |
| 0 | 28.9 | 90.2 | 89.3 | 88.5 | 90.8 | |
| CD4 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | ND | ND | ND | 58.4 | ND | 62.1 |
| ND | ND | ND | 89.1 | ND | 74.6 | |
| ND | 20.5 | 79.6 | 67.2 | 74.2 | 73.7 | |
| ND | 23.3 | 75.3 | 71.5 | 74.3 | 74.9 | |
| CD8 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | ND | ND | ND | 13.2 | ND | 8.3 |
| ND | ND | ND | 7.2 | ND | 19.1 | |
| ND | 17.9 | 8.7 | 15.6 | 14.7 | 16.4 | |
| ND | 12.5 | 10.9 | 11.7 | 16.2 | 12.4 | |
| CD45RA+ T cells | ||||||
| R-350 | ||||||
| R-352 | ND | 82.1 | 98.2 | 95.4 | 97.5 | 86.9 |
| ND | 85.2 | 97.2 | 94.3 | 98.1 | 84.9 | |
| Parameter . | Pretransplantation . | Months Posttransplantation . | ||||
|---|---|---|---|---|---|---|
| . | . | 1 . | 2 . | 3 . | 4 . | 5 . |
| Lymphocytes (per μL) | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 3,658 | ND | ND | 4,154 | ND | 3,962 |
| 734 | ND | ND | 10,492 | ND | 12,366 | |
| 1,062 | 1,050 | 8,624 | 8,786 | 7,708 | 7,100 | |
| 874 | 986 | 8,316 | 4,251 | 4,408 | 4,464 | |
| Phenotype (%) | ||||||
| B | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 17.5 | ND | ND | 8.1 | ND | 11.2 |
| 46.5 | ND | ND | 1.8 | ND | 4.1 | |
| 83.7 | 37.5 | 4.7 | 3.5 | 5.5 | 6.3 | |
| 42.8 | 40.8 | 3.7 | 6.8 | 5.2 | 7.1 | |
| CD3 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | 54.6 | ND | ND | 76.1 | ND | 78.7 |
| 3.4 | ND | ND | 89.9 | ND | 90.6 | |
| 0 | 36.8 | 91.8 | 90.4 | 83.9 | 92.2 | |
| 0 | 28.9 | 90.2 | 89.3 | 88.5 | 90.8 | |
| CD4 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | ND | ND | ND | 58.4 | ND | 62.1 |
| ND | ND | ND | 89.1 | ND | 74.6 | |
| ND | 20.5 | 79.6 | 67.2 | 74.2 | 73.7 | |
| ND | 23.3 | 75.3 | 71.5 | 74.3 | 74.9 | |
| CD8 | ||||||
| Normal | ||||||
| R-16 | ||||||
| R-350 | ||||||
| R-352 | ND | ND | ND | 13.2 | ND | 8.3 |
| ND | ND | ND | 7.2 | ND | 19.1 | |
| ND | 17.9 | 8.7 | 15.6 | 14.7 | 16.4 | |
| ND | 12.5 | 10.9 | 11.7 | 16.2 | 12.4 | |
| CD45RA+ T cells | ||||||
| R-350 | ||||||
| R-352 | ND | 82.1 | 98.2 | 95.4 | 97.5 | 86.9 |
| ND | 85.2 | 97.2 | 94.3 | 98.1 | 84.9 | |
“Normal” is the normal age-matched littermate of R-16.
Abbreviation: ND, not determined.