Table 4. Analyses of EFS From Date of CR... | American Society of Hematology

Table 4.

Analyses of EFS From Date of CR

Variable	Median EFS^4-150 (95% CI)	Univariate P Value^4-151	Multivariate P Value
inv16 or t(8; 21)	None [62, −]	.086	NS
Complex −5, −7	20 [14, 24]	<.001	<.001
Other abnormal or IM	41 [34, 51]	<.001	<.001
Normal karyotype	83 [70, 129]	<.001	—
PS ≤ 2	55 [43, 63]	.006	.005
PS > 2	24.5 [16, 75]		—
IA	70 [48, 127]	.13	—
IA + G	79 [63, 99]	.008	NS
F + A	27 [19, 61]	.022	NS
FLAG	42 [30, 63]	.27	NS
FLAG + Ida	36 [27, 43]	.001	NS
RAEB	22.5 [18-87]	.017	NS
RAEB-t	55 [36-77]	.78	NS
AML	55 [43-68]	.26	—
Age	Decreases with increasing age, effect disappears by 40 wk post-CR	<.001	.033
AHD	Decreases with length of AHD up to plateau at AHD of 10-20 mo	<.001	.017

Variable	Median EFS^4-150 (95% CI)	Univariate P Value^4-151	Multivariate P Value
inv16 or t(8; 21)	None [62, −]	.086	NS
Complex −5, −7	20 [14, 24]	<.001	<.001
Other abnormal or IM	41 [34, 51]	<.001	<.001
Normal karyotype	83 [70, 129]	<.001	—
PS ≤ 2	55 [43, 63]	.006	.005
PS > 2	24.5 [16, 75]		—
IA	70 [48, 127]	.13	—
IA + G	79 [63, 99]	.008	NS
F + A	27 [19, 61]	.022	NS
FLAG	42 [30, 63]	.27	NS
FLAG + Ida	36 [27, 43]	.001	NS
RAEB	22.5 [18-87]	.017	NS
RAEB-t	55 [36-77]	.78	NS
AML	55 [43-68]	.26	—
Age	Decreases with increasing age, effect disappears by 40 wk post-CR	<.001	.033
AHD	Decreases with length of AHD up to plateau at AHD of 10-20 mo	<.001	.017

Abbreviation: NS, not significant.

EFS measured in weeks.

Log-rank test.