Table 1.

CGD Patients Receiving IFN-γ, Subgroups, Oxidative Function Previous to IFN-γ, and Randomization Dose. The Patient CE Is a Hyperlyonized Carrier of X-Linked CGD Yet Expressing a CGD Phenotype

Patient/Age/GenderCGD TypefMLP-Induced CLNBT % Pos CellsRandomization Dose
AA A470 <1% 0 High 
26/F     
MA 33/M A470 <1% 0 High 
EF A?0, not specified <1% 0 High 
6/F     
HA X910 <1% 0 High 
17/M     
CE X91+ Minute ∼8% 4 High 
43/F     
 Hyperlyonized female carrier    
LG A670 <1% 0 Low 
16/F     
TW X910 <1% 0 Low 
9/M     
AW X910 <1% 0 Low 
17/M     
PA A470 <1% 0 Low 
22/M     
PE X910 <1% 0 Low 
7/M     
Patient/Age/GenderCGD TypefMLP-Induced CLNBT % Pos CellsRandomization Dose
AA A470 <1% 0 High 
26/F     
MA 33/M A470 <1% 0 High 
EF A?0, not specified <1% 0 High 
6/F     
HA X910 <1% 0 High 
17/M     
CE X91+ Minute ∼8% 4 High 
43/F     
 Hyperlyonized female carrier    
LG A670 <1% 0 Low 
16/F     
TW X910 <1% 0 Low 
9/M     
AW X910 <1% 0 Low 
17/M     
PA A470 <1% 0 Low 
22/M     
PE X910 <1% 0 Low 
7/M     

Abbreviations: F, female; M, male; X indicates X-linked and A is autosomal recessive inheritance; 91, 47, and 67 indicate the defective “phox” protein; superscript symbols indicate 0, undetectable “phox” protein; +, normal expression of “phox” protein on Western blot (in this case only the expression of her defect gene).

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