Total Progenitor Collection by Treatment Cohort
| Treatment Cohort . | A . | B . | C . | D . | E . |
|---|---|---|---|---|---|
| r-metHuSCF ( μg/kg/d) | 0 | 5 | 10 | 15 | 20 |
| Filgrastim ( μg/kg/d) | 10 | 10 | 10 | 10 | 10 |
| (N = 10) | (N = 6) | (N = 6) | (N = 7) | (N = 6) | |
| CD34+ cells (×106/kg) | |||||
| Median | 3.02 | 3.92 | 2.65 | 3.32 | 0.37 |
| Range | (0.03-20.68) | (0.09-5.84) | (1.03-6.84) | (1.40-12.04) | (0.10-5.90) |
| GM-CFC (×104/kg) | |||||
| Median | 19.21 | 32.37 | 32.47 | 65.89 | 4.11 |
| Range | (0.10-123.07) | (6.34-95.68) | (7.97-121.0) | (26.73-223.76) | (0.13-16.47) |
| BFU-E (×104/kg) | |||||
| Median | 16.89 | 54.19 | 75.60 | 122.71 | 6.93 |
| Range | (0.36-131.55) | (4.79-171.95) | (27.14-161.31) | (23.07-601.46) | (0.00-46.86) |
| MNC (×109/L) | |||||
| Median | 7.55 | 9.31 | 6.95 | 7.41 | 6.50 |
| Range | (2.94-22.42) | (2.21-13.12) | (3.37-10.99) | (5.45-11.58) | (4.81-11.24) |
| Treatment Cohort . | A . | B . | C . | D . | E . |
|---|---|---|---|---|---|
| r-metHuSCF ( μg/kg/d) | 0 | 5 | 10 | 15 | 20 |
| Filgrastim ( μg/kg/d) | 10 | 10 | 10 | 10 | 10 |
| (N = 10) | (N = 6) | (N = 6) | (N = 7) | (N = 6) | |
| CD34+ cells (×106/kg) | |||||
| Median | 3.02 | 3.92 | 2.65 | 3.32 | 0.37 |
| Range | (0.03-20.68) | (0.09-5.84) | (1.03-6.84) | (1.40-12.04) | (0.10-5.90) |
| GM-CFC (×104/kg) | |||||
| Median | 19.21 | 32.37 | 32.47 | 65.89 | 4.11 |
| Range | (0.10-123.07) | (6.34-95.68) | (7.97-121.0) | (26.73-223.76) | (0.13-16.47) |
| BFU-E (×104/kg) | |||||
| Median | 16.89 | 54.19 | 75.60 | 122.71 | 6.93 |
| Range | (0.36-131.55) | (4.79-171.95) | (27.14-161.31) | (23.07-601.46) | (0.00-46.86) |
| MNC (×109/L) | |||||
| Median | 7.55 | 9.31 | 6.95 | 7.41 | 6.50 |
| Range | (2.94-22.42) | (2.21-13.12) | (3.37-10.99) | (5.45-11.58) | (4.81-11.24) |