Expression of RET Proto-Oncogene and GDNFR-α in AML
| Diagnosis . | Expression of . | |
|---|---|---|
| . | RET . | GNDFR-α . |
| . | (no. positive/no. tested) . | (no. positive/no. tested) . |
| AML | 32/53 | 1/42 |
| M0 | 0/3 | 0/2 |
| M1 | 5/13 | 0/10 |
| M2 | 3/4 | 0/3 |
| M3 | 6/7 | 0/5 |
| M4 | 10/14 | 0/12 |
| M5 | 7/10 | 0/8 |
| M6 | 0/1 | 0/1 |
| M7 | 1/1 | 1/1 |
| MBC | 3/5 | 0/4 |
| CML | 2/3 | 0/2 |
| PV | 0/1 | 0/1 |
| IM | 1/1 | 0/1 |
| Diagnosis . | Expression of . | |
|---|---|---|
| . | RET . | GNDFR-α . |
| . | (no. positive/no. tested) . | (no. positive/no. tested) . |
| AML | 32/53 | 1/42 |
| M0 | 0/3 | 0/2 |
| M1 | 5/13 | 0/10 |
| M2 | 3/4 | 0/3 |
| M3 | 6/7 | 0/5 |
| M4 | 10/14 | 0/12 |
| M5 | 7/10 | 0/8 |
| M6 | 0/1 | 0/1 |
| M7 | 1/1 | 1/1 |
| MBC | 3/5 | 0/4 |
| CML | 2/3 | 0/2 |
| PV | 0/1 | 0/1 |
| IM | 1/1 | 0/1 |
RET expression was detected by RT-PCR.
Abbreviations: GDNFR-α, glial cell line-derived neurotrophic factor; MBC, myeloid blast crisis of myeloproliferative disorders; CML, chronic myeloid leukemia; PV, polycythemia vera; IM, idiopathic myelofibrosis.