Frequency of Microsatellite Alterations in B-NHL of the Immunocompetent Host After Clinical Progression
| Type of Lymphoma . | No. of Cases Tested . | Cases Showing Microsatellite Alterations3-150 . | |
|---|---|---|---|
| . | . | At 1 Locus . | At ≥2 Loci . |
| With histologic transformation3-151 | 3 | 0 | 0 |
| Without histologic transformation | 8 | 2 | 0 |
| Type of Lymphoma . | No. of Cases Tested . | Cases Showing Microsatellite Alterations3-150 . | |
|---|---|---|---|
| . | . | At 1 Locus . | At ≥2 Loci . |
| With histologic transformation3-151 | 3 | 0 | 0 |
| Without histologic transformation | 8 | 2 | 0 |
Clinical progression was defined by enlargement of adenopathy, involvement of new sites or stage progression (Lo Coco et al, 1993).26
Five microsatellite loci were tested in each case.
Histologic transformation was defined as B-NHL evolution from follicular to diffuse large cell architecture.