Table 2. Results of VDJ and DJ... | American Society of Hematology

Table 2.

Results of VDJ and DJ Rearrangements in Selected Cases Showing VH, DH, and JH Segments Used

Case	VH Sequence	DH Sequence JH Sequence	VH	DH	JH
Case no. 1	ACTCGGCCGTATATTACTGTGCGA	aagacctcTTTATCACTTCGTCCgt CTACTACGGTATGGACGCCTGGGGCCAAGGGACCA	V3-23^*	DN4	J6
Granta 519	ACACGGCCGTGTATTACTGTGCGAGAG	tTGGCTACAGGTcggagta CTACTTTGACTACTGGGGCCAGGGAACC	VH4-GL7^†	DK4	J4
NCEB-1	ACACGGCCGTGTATTACTGTGCGAGAGA	ttaCCCCGTCtcggacttc TACTACTATTATGGTTTGGACGTCTGGGGCCAAGGGACCG	V3-53^‡	D21/9	J6
Case no. 4 DJ		CAGGGGCTTTTTGTGAAGGGCCCTCCTGCTGTGTGACTACGGTGGTAACgttc TGGGGCCAGGGAACCC	—	D4-23	J5
VDJ	ACACGGCCGTGTATTACTGTGCGA	aagggTCCCGCGGGGGCgaATTTTGACTGGTTATTATccgcct TACTTTGACTACTGGGGCCAGGGAACC	VH-28ρ	DIR2inv DXP1	J4
Case no. 5	ACACGGCTGTGTATTACTGTGCGAGAGA	TCGTAGACACAGTGGCTggtcccccc ATTACTACTACTACTACGGTATGGACGTCTGGGGCCAAGGGACCA	V3-23^2-155	DK5inv DK1	J6

Case	VH Sequence	DH Sequence JH Sequence	VH	DH	JH
Case no. 1	ACTCGGCCGTATATTACTGTGCGA	aagacctcTTTATCACTTCGTCCgt CTACTACGGTATGGACGCCTGGGGCCAAGGGACCA	V3-23^*	DN4	J6
Granta 519	ACACGGCCGTGTATTACTGTGCGAGAG	tTGGCTACAGGTcggagta CTACTTTGACTACTGGGGCCAGGGAACC	VH4-GL7^†	DK4	J4
NCEB-1	ACACGGCCGTGTATTACTGTGCGAGAGA	ttaCCCCGTCtcggacttc TACTACTATTATGGTTTGGACGTCTGGGGCCAAGGGACCG	V3-53^‡	D21/9	J6
Case no. 4 DJ		CAGGGGCTTTTTGTGAAGGGCCCTCCTGCTGTGTGACTACGGTGGTAACgttc TGGGGCCAGGGAACCC	—	D4-23	J5
VDJ	ACACGGCCGTGTATTACTGTGCGA	aagggTCCCGCGGGGGCgaATTTTGACTGGTTATTATccgcct TACTTTGACTACTGGGGCCAGGGAACC	VH-28ρ	DIR2inv DXP1	J4
Case no. 5	ACACGGCTGTGTATTACTGTGCGAGAGA	TCGTAGACACAGTGGCTggtcccccc ATTACTACTACTACTACGGTATGGACGTCTGGGGCCAAGGGACCA	V3-23^2-155	DK5inv DK1	J6

JH sequences are underlined except where there is variation from the germline sequence and n regions are in lowercase. Accession numbers for VH sequences are given together with the percentage of mutation from germline sequence.

M99660 (8%).

†

Z75359 (4%).

‡

X86355 (3%).

ρ Z31688 (1%).

F2-155

M99660 (0%).

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