Long-Term Reconstitution of the PB of SCID Mice With Human Cells After Transplantation With HFBM
| BM-SCID-hu . | % Human CD45+ Cells . | ||
|---|---|---|---|
| Mouse . | 3 Mo. . | 6 Mo. . | 9 Mo. . |
| 119c2 | 44 | 69 | ND |
| 122c1 | 23 | 18 | ND |
| 122c2 | 11 | 13 | ND |
| 122c3 | 4 | 0.5 | ND |
| 125-2 | 14 | 0 | ND |
| 125-3 | 23 | 2 | ND |
| 125-4 | 4 | 7 | ND |
| 125-5 | 19 | 61 | ND |
| 126-2 | 35 | 26 | ND |
| 126-3 | 4 | 0 | ND |
| 126-4 | 4 | 2 | ND |
| 126-5 | 29 | 16 | ND |
| 131b1 | 80 | ND | 16 |
| 131b2 | 4 | ND | 4 |
| 132b3 | 80 | ND | 75 |
| 132b4 | 16 | ND | 8 |
| BM-SCID-hu . | % Human CD45+ Cells . | ||
|---|---|---|---|
| Mouse . | 3 Mo. . | 6 Mo. . | 9 Mo. . |
| 119c2 | 44 | 69 | ND |
| 122c1 | 23 | 18 | ND |
| 122c2 | 11 | 13 | ND |
| 122c3 | 4 | 0.5 | ND |
| 125-2 | 14 | 0 | ND |
| 125-3 | 23 | 2 | ND |
| 125-4 | 4 | 7 | ND |
| 125-5 | 19 | 61 | ND |
| 126-2 | 35 | 26 | ND |
| 126-3 | 4 | 0 | ND |
| 126-4 | 4 | 2 | ND |
| 126-5 | 29 | 16 | ND |
| 131b1 | 80 | ND | 16 |
| 131b2 | 4 | ND | 4 |
| 132b3 | 80 | ND | 75 |
| 132b4 | 16 | ND | 8 |
Irradiated SCID mice were transplanted with cultured HFBM cells and then the PB was analyzed for the presence of human CD45+ cells at 3 months and then at either 6 months or at 9 months after transplantation.
Abbreviation: ND, not done.