Table 3.

Peak Values of Lipid and Lipoprotein by Timepoint of Asparaginase Therapy for Patients With Complete Serial Data

NMean (SD)
PreDuringPost
Triglyceride*†‡ 21 108 (46) 465 (492) 73 (33) 
Cholesterol3-151 21 172 (40) 205 (73) 161 (41) 
LDL 20 121 (33) 97 (49) 97 (29) 
HDL*† 21 36 (13) 37 (15) 46 (11) 
Apo-A1 133 (33) 124 (36) 128 (28) 
Apo-B100†‡ 122 (31) 176 (115) 78 (26) 
NMean (SD)
PreDuringPost
Triglyceride*†‡ 21 108 (46) 465 (492) 73 (33) 
Cholesterol3-151 21 172 (40) 205 (73) 161 (41) 
LDL 20 121 (33) 97 (49) 97 (29) 
HDL*† 21 36 (13) 37 (15) 46 (11) 
Apo-A1 133 (33) 124 (36) 128 (28) 
Apo-B100†‡ 122 (31) 176 (115) 78 (26) 

All values expressed in milligrams per deciliter. Significant differences noted at P < .05.

Abbreviations: Pre, before initiation of asparaginase; During, during 30-week asparaginase therapy; Post, after completion of asparaginase therapy.

F3-150

Significant difference between Pre and During levels.

F3-151

Significant difference between During and Post levels.

F3-152

Significant difference between Pre and Post levels.

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