Table 3.

Prevalence of LMP-1 3′ Deletions in EBV+ Lymphoproliferative Disorders From HIV-Seronegative and HIV-Infected Patients

Hodgkin's DiseaseNon-Hodgkin's Lymphomas
HIV-Seronegative (%)HIV-Seropositive (%)HIV-Seronegative (%)HIV-Seropositive (%)
Full-length LMP-1 18/30 (60) 2/12 (16.7) 3/5 (60) 3/7 (42.9) 
LMP-1 3′ deletion 12/303-150 (40) 10/12 (83.3)3-151 2/5 (40) 4/7 (57.1) 
Hodgkin's DiseaseNon-Hodgkin's Lymphomas
HIV-Seronegative (%)HIV-Seropositive (%)HIV-Seronegative (%)HIV-Seropositive (%)
Full-length LMP-1 18/30 (60) 2/12 (16.7) 3/5 (60) 3/7 (42.9) 
LMP-1 3′ deletion 12/303-150 (40) 10/12 (83.3)3-151 2/5 (40) 4/7 (57.1) 
F3-150

Two of these cases carried a deletion larger than 30 bp.

F3-151

The prevalence of LMP-1 deletions in HIV-related HD is significantly higher (P = .01) than that detected in HD from HIV-seropositive patients.

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