B-B4 Expression in Human B-Cell Non-Hodgkin's Lymphomas/Leukemias and Myeloma/Plasmacytomas as Assessed by FC and Frozen Section IHC
| Diagnosis* . | No. of Positive/ . | |
|---|---|---|
| . | Tested Cases . | |
| . | FC† . | IHC† . |
| B-cell chronic lymphocytic leukemia/prolymphocytic leukemia/small lymphocytic lymphoma | 0/48 | 0/5 |
| Lymphoplasmacytoid lymphoma | 2/2 | — |
| Mantle cell lymphoma | 0/4 | 0/5 |
| Follicular center cell lymphoma | 0/7 | 0/7 |
| Hairy cell leukemia | 0/9 | — |
| Extranodal marginal zone B-cell lymphoma (low-grade B-cell lymphoma of MALT type) | — | 0/2 |
| Plasmacytoma/myeloma | 25/25 | 3/3 |
| Diffuse large B-cell lymphoma | ‡2/11 | 0/14 |
| Burkitt's lymphoma | — | 0/4 |
| High-grade B-cell lymphoma, Burkitt-like | — | 0/1 |
| Diagnosis* . | No. of Positive/ . | |
|---|---|---|
| . | Tested Cases . | |
| . | FC† . | IHC† . |
| B-cell chronic lymphocytic leukemia/prolymphocytic leukemia/small lymphocytic lymphoma | 0/48 | 0/5 |
| Lymphoplasmacytoid lymphoma | 2/2 | — |
| Mantle cell lymphoma | 0/4 | 0/5 |
| Follicular center cell lymphoma | 0/7 | 0/7 |
| Hairy cell leukemia | 0/9 | — |
| Extranodal marginal zone B-cell lymphoma (low-grade B-cell lymphoma of MALT type) | — | 0/2 |
| Plasmacytoma/myeloma | 25/25 | 3/3 |
| Diffuse large B-cell lymphoma | ‡2/11 | 0/14 |
| Burkitt's lymphoma | — | 0/4 |
| High-grade B-cell lymphoma, Burkitt-like | — | 0/1 |
Abbreviations: FC, flow cytometry; IHC, immunohistochemistry.
According to the revised European-American lymphoma classification.2
Cells from 15 B-cell lymphoma/leukemia cases encompassing the different histotypes (3 B-cell chronic lymphocytic leukemia; 2 mantle cell lymphoma; 3 follicular center cell lymphoma; 7 diffuse large B-cell lymphoma) were analyzed by both FC and IHC.
Immunoblastic plasmacytoid.