Immunohistochemical Staining of Cynomolgus Monkey and Human Tissues With G28-5 MoAb and G28-5 sFv-PE40
| Organ . | G28-5 . | G28-5 sFv-PE40 . | Staining Pattern . |
|---|---|---|---|
| Lymph node | +/− to +++ | +/− to +++ | B-cell–dependent areas |
| Spleen | +/− to +++ | +/− to +++ | B-cell–dependent areas |
| Thymus* | ++ to +++ | ++ | Medulla |
| Liver | + to ++ | +/− | Hepatocytes |
| Heart | − | − | |
| Brain | − | − | |
| Stomach | − | − | |
| Colon | − | − |
| Organ . | G28-5 . | G28-5 sFv-PE40 . | Staining Pattern . |
|---|---|---|---|
| Lymph node | +/− to +++ | +/− to +++ | B-cell–dependent areas |
| Spleen | +/− to +++ | +/− to +++ | B-cell–dependent areas |
| Thymus* | ++ to +++ | ++ | Medulla |
| Liver | + to ++ | +/− | Hepatocytes |
| Heart | − | − | |
| Brain | − | − | |
| Stomach | − | − | |
| Colon | − | − |
Abbreviations: −, no staining observed; +/−, mixed areas of no staining and low levels of staining; +, low levels of staining seen throughout; ++, intermediate level of staining; +++, high level of staining.
Data for monkey tissue only.