Table 2.

Influence of Effectors on Oxygen Affinity of Recombinant HbS and E6V(β)/D85K(α)

[DPG] mmol/L[IHP] mmol/L[Cl] mmol L
00.30.40.60.20.4100500
E6V(β)/D85K(α) 10  —  17 23 20 51 13 17 
HbS, P50 10 17  —  24 16* 37* 15† 21† 
[DPG] mmol/L[IHP] mmol/L[Cl] mmol L
00.30.40.60.20.4100500
E6V(β)/D85K(α) 10  —  17 23 20 51 13 17 
HbS, P50 10 17  —  24 16* 37* 15† 21† 

The Hb concentration was 0.5 mmol/L in tetramer.

*

The values are from Himanen et al.38 

†

The values are from Martin de Llano et al.29 

View Large
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal