Table 3.

Hematopoietic Chimerism of Recipient F1 Mice After Parental BM Grafting

RecipientTreatment3-150DonorBM Cells3-151Hematopoietic Chimerism3-152
H-2b/bH-2b/d
B6D2F1 None B6 1 × 105 6.2% 91.0% 
    8.5% 90.4% 
    16.5% 82.4% 
B6D2F1 G-CSF B6 1 × 105 42.0% 55.0% 
    54.0% 40.3% 
    60.2% 38.2% 
RecipientTreatment3-150DonorBM Cells3-151Hematopoietic Chimerism3-152
H-2b/bH-2b/d
B6D2F1 None B6 1 × 105 6.2% 91.0% 
    8.5% 90.4% 
    16.5% 82.4% 
B6D2F1 G-CSF B6 1 × 105 42.0% 55.0% 
    54.0% 40.3% 
    60.2% 38.2% 
F3-150

G-CSF at 25 μg/kg/d was administered subcutaneously with a miniosmotic pump starting on day −14 and BM cells were grafted on day 0.

F3-151

Number of T-cell–depleted B6 BM cells transplanted.

F3-152

Hematopoietic chimerism was examined on day 40. Cells with H-2b/b and H-2b/d phenotypes correspond to donor and recipient, respectively.

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