Table 1.

Effect of G-CSF Administration on the Appearance of Splenic Colonies in Hybrid Resistance

RecipientTreatment*DonorBM CellsDay-8 Splenic Colony
B6D2F1 (−) B6  1 × 105 0.7 ± 1.2 
   2.5 × 105 0.7 ± 1.1 
    1 × 106 2.3 ± 1.5 
B6D2F1 G-CSF B6  1 × 105 3.0 ± 2.0 
   2.5 × 105 10.0 ± 3.9 
    1 × 106 25.3 ± 1.5 
B6D2F1 AGM1 B6  1 × 105 11.3 ± 3.5 
   2.5 × 105 21.0 ± 3.1 
B6 (−) B6  1 × 105 18.0 ± 1.7 
 G-CSF   1 × 105 19.0 ± 5.7 
RecipientTreatment*DonorBM CellsDay-8 Splenic Colony
B6D2F1 (−) B6  1 × 105 0.7 ± 1.2 
   2.5 × 105 0.7 ± 1.1 
    1 × 106 2.3 ± 1.5 
B6D2F1 G-CSF B6  1 × 105 3.0 ± 2.0 
   2.5 × 105 10.0 ± 3.9 
    1 × 106 25.3 ± 1.5 
B6D2F1 AGM1 B6  1 × 105 11.3 ± 3.5 
   2.5 × 105 21.0 ± 3.1 
B6 (−) B6  1 × 105 18.0 ± 1.7 
 G-CSF   1 × 105 19.0 ± 5.7 
*

G-CSF at 25 μg/kg/d was administered subcutaneously with a miniosmotic pump starting on day −14. AGM1 was injected on day −1.

Number of B6 BM cells transplanted.

Number of colonies represents the mean ± SD of three experiments.

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