Adverse Events in 56 Lymphoma Patients Treated With CMI With Roferon-A and rlL-2 Following ABMT
Event . | Toxicity (WHO Grading) . | Total No. and (%) of Patients . | |||
---|---|---|---|---|---|
. | Grade I . | Grade II . | Grade III . | Grade IV . | . |
Nausea/vomiting | 14 | 30 | — | 43 (77) | |
Diarrhea | 23 | 3 | 2 | — | 28 (50) |
Anorexia | — | 6 | 19 | 1 | 26 (46) |
Weight loss | — | 10 | — | — | 10 (18) |
Fever | 2 | 37 | 9 | — | 48 (86) |
Chills | 23 | 9 | — | 32 (57) | |
Fatigue | — | 25 | 20 | 1 | 46 (82) |
Loss of taste | — | 3 | 3 | — | 6 (11) |
Stomatitis | — | 3 | 14 | — | 17 (30) |
Dyspnea (bronchitis) | — | 3 | 1 | — | 4 (7) |
Dry cough | — | 18 | 1 | — | 19 (34) |
Neuromood | 6 | 11 | 2 | — | 19 (34) |
Dry skin | 1 | — | 7 | — | 8 (14) |
Contact dermatitis in the injection site | 2 | 16 | 1 | — | 19 (34) |
Cardiotoxicity | — | — | — | 1 | 1 (∼2) |
Myalgia | — | 13 | 2 | — | 15 (26) |
Alopecia | — | 2 | — | 1 | 3 (∼6) |
Thrombocytopenia | — | 10 | 25 | 10 | 45 (80) |
Anemia | — | 10 | 18 | — | 28 (50) |
Elevation of liver enzymes (ALKP, GGTP) | — | 10 | 18 | — | 28 (50) |
Event . | Toxicity (WHO Grading) . | Total No. and (%) of Patients . | |||
---|---|---|---|---|---|
. | Grade I . | Grade II . | Grade III . | Grade IV . | . |
Nausea/vomiting | 14 | 30 | — | 43 (77) | |
Diarrhea | 23 | 3 | 2 | — | 28 (50) |
Anorexia | — | 6 | 19 | 1 | 26 (46) |
Weight loss | — | 10 | — | — | 10 (18) |
Fever | 2 | 37 | 9 | — | 48 (86) |
Chills | 23 | 9 | — | 32 (57) | |
Fatigue | — | 25 | 20 | 1 | 46 (82) |
Loss of taste | — | 3 | 3 | — | 6 (11) |
Stomatitis | — | 3 | 14 | — | 17 (30) |
Dyspnea (bronchitis) | — | 3 | 1 | — | 4 (7) |
Dry cough | — | 18 | 1 | — | 19 (34) |
Neuromood | 6 | 11 | 2 | — | 19 (34) |
Dry skin | 1 | — | 7 | — | 8 (14) |
Contact dermatitis in the injection site | 2 | 16 | 1 | — | 19 (34) |
Cardiotoxicity | — | — | — | 1 | 1 (∼2) |
Myalgia | — | 13 | 2 | — | 15 (26) |
Alopecia | — | 2 | — | 1 | 3 (∼6) |
Thrombocytopenia | — | 10 | 25 | 10 | 45 (80) |
Anemia | — | 10 | 18 | — | 28 (50) |
Elevation of liver enzymes (ALKP, GGTP) | — | 10 | 18 | — | 28 (50) |