Donor-Dependence of PMN MHC Class II Expression
| Donor . | No. of Samples . | Sampling Period (d)* . | % Positive Cells† . | Average (MFI)‡ . |
|---|---|---|---|---|
| 1 | 4 | 174 | 87.3 ± 1.1 | 255 ± 35 |
| 2 | 3 | 181 | 87.3 ± 3.4 | 189 ± 34 |
| 3 | 3 | 29 | 83.3 ± 0.4 | 193 ± 30 |
| 7 | 5 | 219 | 60.3 ± 1.5 | 47 ± 20 |
| 8 | 3 | 28 | 71.1 ± 0.4 | 29 ± 3 |
| 9 | 3 | 57 | 37.0 ± 2.3 | 29 ± 4 |
| Donor . | No. of Samples . | Sampling Period (d)* . | % Positive Cells† . | Average (MFI)‡ . |
|---|---|---|---|---|
| 1 | 4 | 174 | 87.3 ± 1.1 | 255 ± 35 |
| 2 | 3 | 181 | 87.3 ± 3.4 | 189 ± 34 |
| 3 | 3 | 29 | 83.3 ± 0.4 | 193 ± 30 |
| 7 | 5 | 219 | 60.3 ± 1.5 | 47 ± 20 |
| 8 | 3 | 28 | 71.1 ± 0.4 | 29 ± 3 |
| 9 | 3 | 57 | 37.0 ± 2.3 | 29 ± 4 |
PMN class II induction after 44 hours of culture in the presence of 100 U/mL GM-CSF/IFN-γ is presented for three HLA-DRhigh responders and three HLA-DRlow responders.
The sampling period is the number of days between the first and last sample tested for each donor.
The number of PMN demonstrating class II expression levels above the isotype control are presented as the % positive cells ± SEM.
The MFI represents the level of PMN class II expression above isotype control and is the average for all the samples examined ± SEM.