Analysis of Vλ Genes From Myeloma Patients
| Patient No. . | Ig Light Chain . | VL Family . | GL Donor . | % Homology . | R/S Mutations . | JL . | Tumor-Derived Sequences/Clones Sequenced . | |
|---|---|---|---|---|---|---|---|---|
| . | . | . | . | . | FWR . | CDR . | . | . |
| 10 | λ | Vλ I | DPL2 | 95.6 | 3/3 | 4/2 | Jλ 7 | 12/12 |
| 11 | λ | Vλ I | DPL3 | 91.0 | 3/6 | 9/6 | Jλ 1 | 4/10 |
| 12 | λ | Vλ III | IGLV3S2 | 96.5 | 0/2 | 6/1 | Jλ 7 | 8/8 |
| 13 | λ | Vλ II | DPL11 | 95.9 | 2/4 | 5/0 | Jλ 2 | 6/9 |
| 14 | λ | Vλ II | HSLV2046 | 94.4 | 4/3 | 6/2 | Jλ 2 | 9/11 |
| 15 | λ | Vλ III | DPL23 | 92.9 | 3/6 | 7/2 | Jλ 2 | 8/8 |
| Patient No. . | Ig Light Chain . | VL Family . | GL Donor . | % Homology . | R/S Mutations . | JL . | Tumor-Derived Sequences/Clones Sequenced . | |
|---|---|---|---|---|---|---|---|---|
| . | . | . | . | . | FWR . | CDR . | . | . |
| 10 | λ | Vλ I | DPL2 | 95.6 | 3/3 | 4/2 | Jλ 7 | 12/12 |
| 11 | λ | Vλ I | DPL3 | 91.0 | 3/6 | 9/6 | Jλ 1 | 4/10 |
| 12 | λ | Vλ III | IGLV3S2 | 96.5 | 0/2 | 6/1 | Jλ 7 | 8/8 |
| 13 | λ | Vλ II | DPL11 | 95.9 | 2/4 | 5/0 | Jλ 2 | 6/9 |
| 14 | λ | Vλ II | HSLV2046 | 94.4 | 4/3 | 6/2 | Jλ 2 | 9/11 |
| 15 | λ | Vλ III | DPL23 | 92.9 | 3/6 | 7/2 | Jλ 2 | 8/8 |