Administration of TNFR:Fc Does Not Significantly Influence Plasma Concentrations of LBP During Endotoxemia
| Time (hr) . | LPS Only . | LPS + TNFR:Fc . |
|---|---|---|
| −0.5 | 18.9 ± 1.8 | 20.8 ± 2.5 |
| 0 | 17.5 ± 2.0 | 18.9 ± 3.0 |
| 8 | 58.0 ± 8.7 | 43.8 ± 4.3 |
| 12 | 66.7 ± 6.9 | 54.9 ± 6.1 |
| 24 | 58.9 ± 8.2 | 52.4 ± 6.8 |
| Time (hr) . | LPS Only . | LPS + TNFR:Fc . |
|---|---|---|
| −0.5 | 18.9 ± 1.8 | 20.8 ± 2.5 |
| 0 | 17.5 ± 2.0 | 18.9 ± 3.0 |
| 8 | 58.0 ± 8.7 | 43.8 ± 4.3 |
| 12 | 66.7 ± 6.9 | 54.9 ± 6.1 |
| 24 | 58.9 ± 8.2 | 52.4 ± 6.8 |
Mean ± SE plasma concentrations of LBP (in micrograms per milliliter) after intravenous injection of LPS (lot EC-5; 2 ng/kg) at t = 0 hours in subjects receiving either TNFR:Fc (6 mg/m2; n = 6) starting at t = −0.5 hours or vehicle (n = 6).