Table 1.

Summary of Cytokine Receptors Present on C57BL/6 BM Cells

125I-CytokineAv Receptor No./BM Cell*% Total BM LabeledReference Cell Population% Reference Cells LabeledAv Grains/Reference CellAv Receptor No./Reference Cell
rr′ SCF 200 17.4 Blast 100 130 ± 30 5,900 
rh M-CSF 76 47.3 PMN 77 27 ± 20 80 
rm IL-3 77 61.4 Monocyte 100 25 ± 19 120 
rm GM-CSF 675 60.8 PMN 100 36 ± 9 1,100 
nm G-CSF 110 51.5 PMN 100 99 ± 42 260 
rm IL-6 56 4.5 Monocyte 100 59 ± 32 990 
rh LIF 3.6 Monocyte 71 29 ± 27 190 
rh IL-1α nd nd PMN 94 14 ± 10 nd 
125I-CytokineAv Receptor No./BM Cell*% Total BM LabeledReference Cell Population% Reference Cells LabeledAv Grains/Reference CellAv Receptor No./Reference Cell
rr′ SCF 200 17.4 Blast 100 130 ± 30 5,900 
rh M-CSF 76 47.3 PMN 77 27 ± 20 80 
rm IL-3 77 61.4 Monocyte 100 25 ± 19 120 
rm GM-CSF 675 60.8 PMN 100 36 ± 9 1,100 
nm G-CSF 110 51.5 PMN 100 99 ± 42 260 
rm IL-6 56 4.5 Monocyte 100 59 ± 32 990 
rh LIF 3.6 Monocyte 71 29 ± 27 190 
rh IL-1α nd nd PMN 94 14 ± 10 nd 

All labeling was completely inhibited in the presence of a 100-fold excess of the appropriate unlabeled cytokine.

Abbreviation: nd, not determined.

*

Determined by Scatchard analysis on 5 × 106 C57BL/6 BM cells incubated on ice for 3 hours.

Mean grain counts ± standard deviations of labeled cells.

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