Abrogation of MHC Restriction After Radiation
| BM Donor . | Recipient . | Radiation . | . | Grafted Bones From4-150 . | |||
|---|---|---|---|---|---|---|---|
| . | . | . | . | B6 . | BALB/c . | C3H . | DBA/1 . |
| B6 | DBA/1 | (−) | Cell counts (× 104) | 248.0 ± 231.3 | 28.3 ± 29.1 | 13.0 ± 15.4 | 43.6 ± 45.6 |
| CFU-GM | 708 ± 650 | 75 ± 95 | 23 ± 39 | 200 ± 154 | |||
| B6 | DBA/1 | (+) | Cell counts (× 104) | 16.0 ± 16.24-150 | 1.0 ± 1.4 | 19.5 ± 26.1 | 13.8 ± 21.2 |
| CFU-GM | 108 ± 85 | 2 ± 3 | 123 ± 119 | 170 ± 214 | |||
| BM Donor . | Recipient . | Radiation . | . | Grafted Bones From4-150 . | |||
|---|---|---|---|---|---|---|---|
| . | . | . | . | B6 . | BALB/c . | C3H . | DBA/1 . |
| B6 | DBA/1 | (−) | Cell counts (× 104) | 248.0 ± 231.3 | 28.3 ± 29.1 | 13.0 ± 15.4 | 43.6 ± 45.6 |
| CFU-GM | 708 ± 650 | 75 ± 95 | 23 ± 39 | 200 ± 154 | |||
| B6 | DBA/1 | (+) | Cell counts (× 104) | 16.0 ± 16.24-150 | 1.0 ± 1.4 | 19.5 ± 26.1 | 13.8 ± 21.2 |
| CFU-GM | 108 ± 85 | 2 ± 3 | 123 ± 119 | 170 ± 214 | |||
Grafted bones were irradiated (8Gy) together with recipient mice before BMT.
Data are expressed as the mean ± SD.