ICC-APL-01 protocol: OS, EFS, and CIR estimates
| . | 5-y OS estimate (95% CI) . | P . | 5-y EFS estimate (95% CI) . | P . | 5-y CIR estimate (95% CI) . | P . |
|---|---|---|---|---|---|---|
| HR | 89.4 (83.6-95.5) | .002 | 74.2 (65.7-83.8) | .043 | 17.5 (17.2-17.9) | .276 |
| SR | 98.4 (96.3-100) | 84.3 (77.2-91.7) | 12.1 (11.9-12.4) | |||
| 0-5 y | 100 (100-100) | .548 | 78.0 (63.7-95.5) | .865 | 13.3 (12.2-14.4) | .968 |
| 6-12 y | 94.3 (90.0-98.9) | 80.9 (72.9-89.8) | 14.7 (14.4-15.0) | |||
| >12 y | 93.0 (88.1-98.2) | 79.4 (71.2-88.5) | 14.0 (13.7-14.4) | |||
| Female | 92.2 (87.6-97.0) | .072 | 82.3 (75.3-90) | .56 | 10.6 (10.4-10.9) | .203 |
| Male | 97.2 (94.1-100) | 77.2 (69.0-86.3) | 18.4 (18.1-18.8) | |||
| PML/RARĪ±: bcr1+bcr2 | 96 (92.3-99.9) | .072 | 80.4 (72.5-89.2) | .581 | 15.3 (14.9-15.6) | .736 |
| bcr3 | 91.9 (86.5-97.5) | 79.7 (71.2-89.2) | 12.0 (11.7-12.3) |
| . | 5-y OS estimate (95% CI) . | P . | 5-y EFS estimate (95% CI) . | P . | 5-y CIR estimate (95% CI) . | P . |
|---|---|---|---|---|---|---|
| HR | 89.4 (83.6-95.5) | .002 | 74.2 (65.7-83.8) | .043 | 17.5 (17.2-17.9) | .276 |
| SR | 98.4 (96.3-100) | 84.3 (77.2-91.7) | 12.1 (11.9-12.4) | |||
| 0-5 y | 100 (100-100) | .548 | 78.0 (63.7-95.5) | .865 | 13.3 (12.2-14.4) | .968 |
| 6-12 y | 94.3 (90.0-98.9) | 80.9 (72.9-89.8) | 14.7 (14.4-15.0) | |||
| >12 y | 93.0 (88.1-98.2) | 79.4 (71.2-88.5) | 14.0 (13.7-14.4) | |||
| Female | 92.2 (87.6-97.0) | .072 | 82.3 (75.3-90) | .56 | 10.6 (10.4-10.9) | .203 |
| Male | 97.2 (94.1-100) | 77.2 (69.0-86.3) | 18.4 (18.1-18.8) | |||
| PML/RARĪ±: bcr1+bcr2 | 96 (92.3-99.9) | .072 | 80.4 (72.5-89.2) | .581 | 15.3 (14.9-15.6) | .736 |
| bcr3 | 91.9 (86.5-97.5) | 79.7 (71.2-89.2) | 12.0 (11.7-12.3) |