Demographic and ADAMTS13 activity data in patients who died or survived
| . | TTP episodes (n = 312) . | ||
|---|---|---|---|
| . | Survived (n = 280) . | Died (n = 32) . | P value . |
| Age (range) | 46 (11-85) | 51 (22-88) | .11* |
| Female (%) | 192 (69) | 20 (63) | .55† |
| Ethnicity (%) | |||
| Afro-Caribbean | 61 (22) | 7 (22) | >.99† |
| Asian | 18 (6) | 2 (6) | >.99† |
| White | 149 (53) | 16 (50) | .85† |
| Mixed/other | 16 (6) | 4 (13) | .14† |
| Not stated | 36 (13) | 3 (9) | .78† |
| Median ADAMTS13 activity (range), % | <5 (<5-18) | <5 (<5-18) | .92* |
| Median anti-ADAMTS13 IgG antibody level (range), % | 39 (1-189) | 66 (4-164) | .004* |
| Median ADAMTS13 antigen level (range) | 4.2 (0.5-146) | 1.6 (0.5-21.5) | .0007* |
| Relapsed TTP (%) | 37 (13.2) | 2 (6.3) | .39† |
| . | TTP episodes (n = 312) . | ||
|---|---|---|---|
| . | Survived (n = 280) . | Died (n = 32) . | P value . |
| Age (range) | 46 (11-85) | 51 (22-88) | .11* |
| Female (%) | 192 (69) | 20 (63) | .55† |
| Ethnicity (%) | |||
| Afro-Caribbean | 61 (22) | 7 (22) | >.99† |
| Asian | 18 (6) | 2 (6) | >.99† |
| White | 149 (53) | 16 (50) | .85† |
| Mixed/other | 16 (6) | 4 (13) | .14† |
| Not stated | 36 (13) | 3 (9) | .78† |
| Median ADAMTS13 activity (range), % | <5 (<5-18) | <5 (<5-18) | .92* |
| Median anti-ADAMTS13 IgG antibody level (range), % | 39 (1-189) | 66 (4-164) | .004* |
| Median ADAMTS13 antigen level (range) | 4.2 (0.5-146) | 1.6 (0.5-21.5) | .0007* |
| Relapsed TTP (%) | 37 (13.2) | 2 (6.3) | .39† |