Management given at the time of bleeding
| Management given . | Apixaban . | Rivaroxaban . | Total . | P . |
|---|---|---|---|---|
| Type of PCC given, n (%) | .23 | |||
| Confidex | 23 (60.0) | 21 (46.7) | 44 (52.4) | |
| Ocplex | 15 (38.5) | 24 (53.3) | 39 (46.4) | |
| Undefined | 1 (2.6) | 0 (0.0) | 1 (1.2) | |
| PCC dose, IU factor IX, median (IQR) | ||||
| Total dose | 2000 (2000-2000) | 2000 (1500-2000) | 2000 (1500-2000) | .26 |
| Dose, IU/kg | 26.7 (22.0-29.9) | 26.7 (20.8-29.4) | 26.7 (21.4-29.9) | .62 |
| Transfusions given, n (%) | ||||
| Red blood cell concentrate | 9 (23.1) | 11 (24.4) | 20 (23.8) | 1.00 |
| Plasma | 2 (5.1) | 8 (17.8) | 10 (11.9) | .10 |
| Platelets | 2 (5.1) | 8 (17.8) | 10 (11.9) | .10 |
| Transfusion units, median (range) | ||||
| Red blood cell concentrate | 0 (0-6) | 0 (0-19) | 0 (0-19) | .66 |
| Plasma | 0 (0-2) | 0 (0-12) | 0 (0-12) | .06 |
| Platelets | 0 (0-1) | 0 (0-4) | 0 (0-4) | .07 |
| Any intervention, n (%) | .76 | |||
| None | 25 (64.1) | 31 (68.9) | 56 (66.6) | |
| Craniotomy | 7 (18.0) | 6 (13.3) | 13 (15.5) | |
| Gastroscopy | 4 (10.3) | 3 (6.7) | 7 (8.3) | |
| Embolization* | 2 (5.1) | 2 (4.4) | 4 (4.8) | |
| Laparotomy† | 0 (0.0) | 2 (4.4) | 2 (2.4) | |
| Fasciotomy | 2 (2.6) | 0 (0.0) | 1 (1.2) | |
| Thoracotomy‡ | 0 (0.0) | 1 (2.2) | 1 (1.2) | |
| Management given . | Apixaban . | Rivaroxaban . | Total . | P . |
|---|---|---|---|---|
| Type of PCC given, n (%) | .23 | |||
| Confidex | 23 (60.0) | 21 (46.7) | 44 (52.4) | |
| Ocplex | 15 (38.5) | 24 (53.3) | 39 (46.4) | |
| Undefined | 1 (2.6) | 0 (0.0) | 1 (1.2) | |
| PCC dose, IU factor IX, median (IQR) | ||||
| Total dose | 2000 (2000-2000) | 2000 (1500-2000) | 2000 (1500-2000) | .26 |
| Dose, IU/kg | 26.7 (22.0-29.9) | 26.7 (20.8-29.4) | 26.7 (21.4-29.9) | .62 |
| Transfusions given, n (%) | ||||
| Red blood cell concentrate | 9 (23.1) | 11 (24.4) | 20 (23.8) | 1.00 |
| Plasma | 2 (5.1) | 8 (17.8) | 10 (11.9) | .10 |
| Platelets | 2 (5.1) | 8 (17.8) | 10 (11.9) | .10 |
| Transfusion units, median (range) | ||||
| Red blood cell concentrate | 0 (0-6) | 0 (0-19) | 0 (0-19) | .66 |
| Plasma | 0 (0-2) | 0 (0-12) | 0 (0-12) | .06 |
| Platelets | 0 (0-1) | 0 (0-4) | 0 (0-4) | .07 |
| Any intervention, n (%) | .76 | |||
| None | 25 (64.1) | 31 (68.9) | 56 (66.6) | |
| Craniotomy | 7 (18.0) | 6 (13.3) | 13 (15.5) | |
| Gastroscopy | 4 (10.3) | 3 (6.7) | 7 (8.3) | |
| Embolization* | 2 (5.1) | 2 (4.4) | 4 (4.8) | |
| Laparotomy† | 0 (0.0) | 2 (4.4) | 2 (2.4) | |
| Fasciotomy | 2 (2.6) | 0 (0.0) | 1 (1.2) | |
| Thoracotomy‡ | 0 (0.0) | 1 (2.2) | 1 (1.2) | |