Mouse studies on the role of tumor-derived TF+ MVs in cancer-associated thrombosis
| Tumor type . | Mouse . | Tumor site . | Conclusion . | Reference . |
|---|---|---|---|---|
| Human colorectal cancer cell lines | SCID | Subcutaneous | Human TF antigen in plasma | 83 |
| Human pancreatic cancer cell line L3.6pl | Nude | Orthotopic | Human TF MV activity and TAT in plasma | 84 |
| Mouse pancreatic cancer cell line Panc02 and lung cancer cell line LLC1 | C57BL/6J | Subcutaneous | Increased thrombosis in mesenteric ferric chloride model | 57 |
| Human pancreatic cancer cell lines HPAF-II and HPAC | Nude | Subcutaneous and orthotopic | Human TF antigen and MV activity and TAT in plasma | 67 |
| Mouse pancreatic cancer cell line Panc02 | C57BL/6J | Subcutaneous | Increased thrombosis in IVC stenosis model | 85 |
| Human pancreatic cancer cell lines BxPc-3 and L3.6pl | Nude | Orthotopic | Increased thrombosis in IVC stenosis model | 54 |
| Human pancreatic cancer cell line BxPc-3 | Nude | Orthotopic | Human TF+ MVs increase thrombosis in IVC stasis model | 30 |
| Tumor type . | Mouse . | Tumor site . | Conclusion . | Reference . |
|---|---|---|---|---|
| Human colorectal cancer cell lines | SCID | Subcutaneous | Human TF antigen in plasma | 83 |
| Human pancreatic cancer cell line L3.6pl | Nude | Orthotopic | Human TF MV activity and TAT in plasma | 84 |
| Mouse pancreatic cancer cell line Panc02 and lung cancer cell line LLC1 | C57BL/6J | Subcutaneous | Increased thrombosis in mesenteric ferric chloride model | 57 |
| Human pancreatic cancer cell lines HPAF-II and HPAC | Nude | Subcutaneous and orthotopic | Human TF antigen and MV activity and TAT in plasma | 67 |
| Mouse pancreatic cancer cell line Panc02 | C57BL/6J | Subcutaneous | Increased thrombosis in IVC stenosis model | 85 |
| Human pancreatic cancer cell lines BxPc-3 and L3.6pl | Nude | Orthotopic | Increased thrombosis in IVC stenosis model | 54 |
| Human pancreatic cancer cell line BxPc-3 | Nude | Orthotopic | Human TF+ MVs increase thrombosis in IVC stasis model | 30 |
TAT, thrombin-antithrombin [complex].