Table 2.

Logistic regression analysis to identify predictors of subjective overreporting by ≥5 days in ≥50% of study months (comparison group: all others)

VariableUnivariable analysisMultivariable analysis*
OR95% CIPOR95% CIP
Age (per year) 1.07 1.018-1.125 .0076 1.079 0.991-1.175 .0788 
Race/ethnicity       
 Non-Hispanic white 1.000   1.000   
 Hispanic 2.733 1.489-5.017 .0012 2.389 1.127-5.064 .0231 
 Asian 2.235 1.011-4.944 .0470 3.121 1.171-8.319 .0229 
 African American 5.471 2.673-11.198 <.0001 5.389 2.274-12.775 .0001 
Sex       
 Male 1.000      
 Female 1.132 0.704-1.821 .6078    
Annual household income, $K       
 ≥50 1.000      
 <50 1.629 0.993-2.671 .0533 1.118 0.574-2.178 .7435 
Maternal education       
 College degree or higher 1.000      
 Less than college degree 1.109 0.877-1.403 .3873    
Paternal education       
 College degree or higher 1.000   1.000   
 Less than college degree 1.43 1.107-1.847 .0062 1.417 1.001-2.007 .0493 
TPMT genotype       
 Wild type 1.000   1.000   
 Heterozygous/homozygous 0.878 0.360-2.144 .7757 0.879 0.501-1.543 .6533 
NCI risk classification       
 Standard 1.000      
 High 1.526 0.963-2.418 .0721 0.887 0.419-1.876 .7534 
 6MP Dose Intensity (per unit increase) 3.914 1.386-11.051 .0100 1.276 0.363-4.480 .7038 
 Red cell TGN level (per unit increase) 0.998 0.995-1.001 .1881    
6MP MEMS adherence rate       
 ≥95% (adherent) 1.000   1.000   
 <95% (nonadherent) 9.651 5.613-16.595 <.001 9.407 5.066-17.467 <.001 
VariableUnivariable analysisMultivariable analysis*
OR95% CIPOR95% CIP
Age (per year) 1.07 1.018-1.125 .0076 1.079 0.991-1.175 .0788 
Race/ethnicity       
 Non-Hispanic white 1.000   1.000   
 Hispanic 2.733 1.489-5.017 .0012 2.389 1.127-5.064 .0231 
 Asian 2.235 1.011-4.944 .0470 3.121 1.171-8.319 .0229 
 African American 5.471 2.673-11.198 <.0001 5.389 2.274-12.775 .0001 
Sex       
 Male 1.000      
 Female 1.132 0.704-1.821 .6078    
Annual household income, $K       
 ≥50 1.000      
 <50 1.629 0.993-2.671 .0533 1.118 0.574-2.178 .7435 
Maternal education       
 College degree or higher 1.000      
 Less than college degree 1.109 0.877-1.403 .3873    
Paternal education       
 College degree or higher 1.000   1.000   
 Less than college degree 1.43 1.107-1.847 .0062 1.417 1.001-2.007 .0493 
TPMT genotype       
 Wild type 1.000   1.000   
 Heterozygous/homozygous 0.878 0.360-2.144 .7757 0.879 0.501-1.543 .6533 
NCI risk classification       
 Standard 1.000      
 High 1.526 0.963-2.418 .0721 0.887 0.419-1.876 .7534 
 6MP Dose Intensity (per unit increase) 3.914 1.386-11.051 .0100 1.276 0.363-4.480 .7038 
 Red cell TGN level (per unit increase) 0.998 0.995-1.001 .1881    
6MP MEMS adherence rate       
 ≥95% (adherent) 1.000   1.000   
 <95% (nonadherent) 9.651 5.613-16.595 <.001 9.407 5.066-17.467 <.001 

Bold font indicates significance.

OR, odds ratio.

*

Multivariable analysis includes variables from univariable analysis that were associated with overreporting 6MP intake by P < .1, adjusted for TPMT.

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