Response of patients with PRCA to immunosuppression
Agent used . | Patients treated (responders/total) . | % responding . |
---|---|---|
Corticosteroids | 50/128 | 39% |
Cytotoxic agents | 46/113 | 41% |
Cyclosporine A | 37/48 | 77% |
Antithymocyte globulin | 10/19 | 53% |
Multiple agents | 91/133 | 68% |
Agent used . | Patients treated (responders/total) . | % responding . |
---|---|---|
Corticosteroids | 50/128 | 39% |
Cytotoxic agents | 46/113 | 41% |
Cyclosporine A | 37/48 | 77% |
Antithymocyte globulin | 10/19 | 53% |
Multiple agents | 91/133 | 68% |
Total patients treated, n = 195 (many patients did not respond to treatment or suffered relapses, so 1 patient may be included in more than one treatment modality); primary PRCA, n = 137; secondary PRCA (n = 58). Modified from Lipton et al.44 Results pooled from 4 series.1,13,26,27