Mouse strains used in the study
Mouse identification . | Genotype . |
---|---|
LC | Lck-cre+ |
LCR | Lck-cre+ LSL-KrasG12D |
LCD | Lck-cre+ LSL-DNMAML-GFP+/− |
LCDR | Lck-cre+ LSL-KrasG12D LSL-DNMAML-GFP+/− |
LCDD | Lck-cre+ LSL-DNMAML-GFP+/+ |
LCDDR | Lck-cre+ LSL-KrasG12D LSL-DNMAML-GFP+/+ |
Mouse identification . | Genotype . |
---|---|
LC | Lck-cre+ |
LCR | Lck-cre+ LSL-KrasG12D |
LCD | Lck-cre+ LSL-DNMAML-GFP+/− |
LCDR | Lck-cre+ LSL-KrasG12D LSL-DNMAML-GFP+/− |
LCDD | Lck-cre+ LSL-DNMAML-GFP+/+ |
LCDDR | Lck-cre+ LSL-KrasG12D LSL-DNMAML-GFP+/+ |
LSL-KrasG12D refers to a transgene containing a floxed-stop cassette upstream of the KrasG12D oncogene inserted into the endogenous Kras locus. LSL-DNMAML-GFP refers to a transgene containing a floxed-stop cassette upstream of the DNMAML peptide/GFP fusion protein inserted into the Rosa26 locus.