Table 1 Patient and donor demographics... | American Society of Hematology

Table 1

Patient and donor demographics and transplant outcome

Patient	Age, y	Prior therapies	Prior autograft	Prior rituximab	Donor	Disease status	TNFRSF14 mutation	TNFRSF14 deletion	Acute GVHD*	Chronic GVHD	Outcome
1	48	8	Yes	Yes	Sibling	Not CR	Yes	Yes	NE	NE	Died PD
1	48	8	Yes	Yes	Sibling	Not CR	Yes	Yes	NE	NE	D+12
2	43	5	No	No	Sibling	Not CR	Yes	Yes	Yes	Yes	Died GVHD
2	43	5	No	No	Sibling	Not CR	Yes	Yes	Yes	Yes	D+217
3	66	5	No	Yes	Unrelated	Not CR	Yes	Yes	Yes	Yes	Died GVHD
3	66	5	No	Yes	Unrelated	Not CR	Yes	Yes	Yes	Yes	D+378
4	61	4	No	Yes	Unrelated	Not CR	Yes	No	Yes	NE	Died GVHD
4	61	4	No	Yes	Unrelated	Not CR	Yes	No	Yes	NE	D+87
5	57	3	Yes	Yes	Unrelated	Not CR	Yes	No	Yes	Yes	Died GVHD
5	57	3	Yes	Yes	Unrelated	Not CR	Yes	No	Yes	Yes	D+159
6	54	3	No	Yes	Unrelated	Not CR	No	Yes	Yes	Yes	Died GVHD
6	54	3	No	Yes	Unrelated	Not CR	No	Yes	Yes	Yes	D+232
7	49	6	Yes	Yes	Sibling	CR	No	Yes	Yes	No	Died PD
7	49	6	Yes	Yes	Sibling	CR	No	Yes	Yes	No	D+138
8	49	8	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	Alive CR
8	49	8	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	D+2726
9	64	3	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	Died GVHD
9	64	3	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	D+1714
10	52	3	Yes	No	Sibling	CR	Yes	No	No	Yes	Alive CR
10	52	3	Yes	No	Sibling	CR	Yes	No	No	Yes	D+2230
11	60	7	No	Yes	Unrelated	CR	Yes	Yes	No	No	Alive CR
11	60	7	No	Yes	Unrelated	CR	Yes	Yes	No	No	D+2292
12	49	4	Yes	Yes	Unrelated	CR	No	Yes	No	No	Alive CR
12	49	4	Yes	Yes	Unrelated	CR	No	Yes	No	No	D+1359
13	61	5	No	Yes	Sibling	Not CR	No	No	Yes	No	Alive CR
13	61	5	No	Yes	Sibling	Not CR	No	No	Yes	No	D+3206
14	54	6	Yes	No	Sibling	Not CR	No	No	Yes	No	Died PD
14	54	6	Yes	No	Sibling	Not CR	No	No	Yes	No	D+160
15	51	4	No	Yes	Sibling	CR	No	No	No	Yes	Alive CR
15	51	4	No	Yes	Sibling	CR	No	No	No	Yes	D+2313
16	53	5	Yes	Yes	Sibling	CR	No	No	No	Yes	Alive CR
16	53	5	Yes	Yes	Sibling	CR	No	No	No	Yes	D+2988
17	34	8	Yes	Yes	Sibling	Not CR	No	No	No	No	Alive CR†
17	34	8	Yes	Yes	Sibling	Not CR	No	No	No	No	D+4810
18	49	3	No	Yes	Sibling	Not CR	No	No	No	No	Alive CR‡
18	49	3	No	Yes	Sibling	Not CR	No	No	No	No	D+3207
19	50	5	No	Yes	Sibling	Not CR	No	No	No	No	Died CR§
19	50	5	No	Yes	Sibling	Not CR	No	No	No	No	D+582
20	34	3	No	Yes	Sibling	CR	No	No	No	No	Alive CR
20	34	3	No	Yes	Sibling	CR	No	No	No	No	D+1728
21	46	7	Yes	Yes	Unrelated	Not CR	No	No	No	No	Alive CR
21	46	7	Yes	Yes	Unrelated	Not CR	No	No	No	No	D+1205
22	30	3	No	No	Sibling	CR	No	No	No	Yes	Alive CR
22	30	3	No	No	Sibling	CR	No	No	No	Yes	D+3611
23	46	4	Yes	No	Sibling	CR	No	No	No	No	Alive CR
23	46	4	Yes	No	Sibling	CR	No	No	No	No	D+4312

Patient	Age, y	Prior therapies	Prior autograft	Prior rituximab	Donor	Disease status	TNFRSF14 mutation	TNFRSF14 deletion	Acute GVHD*	Chronic GVHD	Outcome
1	48	8	Yes	Yes	Sibling	Not CR	Yes	Yes	NE	NE	Died PD
1	48	8	Yes	Yes	Sibling	Not CR	Yes	Yes	NE	NE	D+12
2	43	5	No	No	Sibling	Not CR	Yes	Yes	Yes	Yes	Died GVHD
2	43	5	No	No	Sibling	Not CR	Yes	Yes	Yes	Yes	D+217
3	66	5	No	Yes	Unrelated	Not CR	Yes	Yes	Yes	Yes	Died GVHD
3	66	5	No	Yes	Unrelated	Not CR	Yes	Yes	Yes	Yes	D+378
4	61	4	No	Yes	Unrelated	Not CR	Yes	No	Yes	NE	Died GVHD
4	61	4	No	Yes	Unrelated	Not CR	Yes	No	Yes	NE	D+87
5	57	3	Yes	Yes	Unrelated	Not CR	Yes	No	Yes	Yes	Died GVHD
5	57	3	Yes	Yes	Unrelated	Not CR	Yes	No	Yes	Yes	D+159
6	54	3	No	Yes	Unrelated	Not CR	No	Yes	Yes	Yes	Died GVHD
6	54	3	No	Yes	Unrelated	Not CR	No	Yes	Yes	Yes	D+232
7	49	6	Yes	Yes	Sibling	CR	No	Yes	Yes	No	Died PD
7	49	6	Yes	Yes	Sibling	CR	No	Yes	Yes	No	D+138
8	49	8	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	Alive CR
8	49	8	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	D+2726
9	64	3	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	Died GVHD
9	64	3	No	Yes	Unrelated	CR	No	Yes	Yes	Yes	D+1714
10	52	3	Yes	No	Sibling	CR	Yes	No	No	Yes	Alive CR
10	52	3	Yes	No	Sibling	CR	Yes	No	No	Yes	D+2230
11	60	7	No	Yes	Unrelated	CR	Yes	Yes	No	No	Alive CR
11	60	7	No	Yes	Unrelated	CR	Yes	Yes	No	No	D+2292
12	49	4	Yes	Yes	Unrelated	CR	No	Yes	No	No	Alive CR
12	49	4	Yes	Yes	Unrelated	CR	No	Yes	No	No	D+1359
13	61	5	No	Yes	Sibling	Not CR	No	No	Yes	No	Alive CR
13	61	5	No	Yes	Sibling	Not CR	No	No	Yes	No	D+3206
14	54	6	Yes	No	Sibling	Not CR	No	No	Yes	No	Died PD
14	54	6	Yes	No	Sibling	Not CR	No	No	Yes	No	D+160
15	51	4	No	Yes	Sibling	CR	No	No	No	Yes	Alive CR
15	51	4	No	Yes	Sibling	CR	No	No	No	Yes	D+2313
16	53	5	Yes	Yes	Sibling	CR	No	No	No	Yes	Alive CR
16	53	5	Yes	Yes	Sibling	CR	No	No	No	Yes	D+2988
17	34	8	Yes	Yes	Sibling	Not CR	No	No	No	No	Alive CR†
17	34	8	Yes	Yes	Sibling	Not CR	No	No	No	No	D+4810
18	49	3	No	Yes	Sibling	Not CR	No	No	No	No	Alive CR‡
18	49	3	No	Yes	Sibling	Not CR	No	No	No	No	D+3207
19	50	5	No	Yes	Sibling	Not CR	No	No	No	No	Died CR§
19	50	5	No	Yes	Sibling	Not CR	No	No	No	No	D+582
20	34	3	No	Yes	Sibling	CR	No	No	No	No	Alive CR
20	34	3	No	Yes	Sibling	CR	No	No	No	No	D+1728
21	46	7	Yes	Yes	Unrelated	Not CR	No	No	No	No	Alive CR
21	46	7	Yes	Yes	Unrelated	Not CR	No	No	No	No	D+1205
22	30	3	No	No	Sibling	CR	No	No	No	Yes	Alive CR
22	30	3	No	No	Sibling	CR	No	No	No	Yes	D+3611
23	46	4	Yes	No	Sibling	CR	No	No	No	No	Alive CR
23	46	4	Yes	No	Sibling	CR	No	No	No	No	D+4312

CR, complete remission; D, day; DLI, donor lymphocyte infusion; MI, myocardial infarction; NE, not evaluable; PD, progressive disease.

Spontaneous acute excluding DLI-induced.

†

Progressed D+72 given DLI.

‡

Progressed D+85 given DLI.

Died of MI in CR.

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