ISM (n = 83): cumulative probability of disease progression from disease onset according to the presence vs absence of the D816V KIT mutation in BM MSCs
PFS rate, y . | KIT D816V+ MSCs, % . | KIT D816V−MSCs, % . | |||
---|---|---|---|---|---|
All cases . | Cases with multilineage KIT mutation . | ||||
n = 22 . | n = 61 . | P . | n = 18 . | P . | |
10 | 82 ± 8 | 98 ± 2 | .003 | 94 ± 5 | .19 |
20 | 63 ± 12 | 98 ± 2 | <.001 | 94 ± 5 | .07 |
30 | 54 ± 13 | 78 ± 18 | .001 | 63 ± 26 | .08 |
PFS rate, y . | KIT D816V+ MSCs, % . | KIT D816V−MSCs, % . | |||
---|---|---|---|---|---|
All cases . | Cases with multilineage KIT mutation . | ||||
n = 22 . | n = 61 . | P . | n = 18 . | P . | |
10 | 82 ± 8 | 98 ± 2 | .003 | 94 ± 5 | .19 |
20 | 63 ± 12 | 98 ± 2 | <.001 | 94 ± 5 | .07 |
30 | 54 ± 13 | 78 ± 18 | .001 | 63 ± 26 | .08 |
Results expressed as percentage of cases ± 1 standard deviation.