Table 4

ISM (n = 83): cumulative probability of disease progression from disease onset according to the presence vs absence of the D816V KIT mutation in BM MSCs

PFS rate, yKIT D816V+ MSCs, %KIT D816VMSCs, %
All casesCases with multilineage KIT mutation
n = 22n = 61Pn = 18P
10 82 ± 8 98 ± 2 .003 94 ± 5 .19 
20 63 ± 12 98 ± 2 <.001 94 ± 5 .07 
30 54 ± 13 78 ± 18 .001 63 ± 26 .08 
PFS rate, yKIT D816V+ MSCs, %KIT D816VMSCs, %
All casesCases with multilineage KIT mutation
n = 22n = 61Pn = 18P
10 82 ± 8 98 ± 2 .003 94 ± 5 .19 
20 63 ± 12 98 ± 2 <.001 94 ± 5 .07 
30 54 ± 13 78 ± 18 .001 63 ± 26 .08 

Results expressed as percentage of cases ± 1 standard deviation.

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