Median baseline biomarker levels in the JHS, by SCT carrier status
| Biomarker . | Participants, n . | Median concentration (IQR) . | P . | |
|---|---|---|---|---|
| SCT carriers . | Noncarriers . | |||
| Fibrinogen, mg/dL | 2608 | 415 (352-493) | 406 (355-463) | .08 |
| CRP, mg/L | 2866 | 0.31 (0.14-0.66) | 0.26 (0.11-0.57) | .45 |
| D-dimer, μg/mL | 2584 | 0.55 (0.35-0.86) | 0.38 (0.25-0.60) | <.0001 |
| WBC, ×103/μL | 2527 | 5.2 (4.2-6.3) | 5.3 (4.4-6.6) | .29 |
| Platelet count, ×103/μL | 2808 | 243 (208-288) | 245 (207-289) | .19 |
| P-selectin, ng/mL | 2055 | 31.9 (25.9-39.7) | 32.5 (26.0-40.3) | .92 |
| E-selectin, ng/mL | 2065 | 40.8 (27.8-55.9) | 41.3 (29.7-55.6) | .30 |
| Biomarker . | Participants, n . | Median concentration (IQR) . | P . | |
|---|---|---|---|---|
| SCT carriers . | Noncarriers . | |||
| Fibrinogen, mg/dL | 2608 | 415 (352-493) | 406 (355-463) | .08 |
| CRP, mg/L | 2866 | 0.31 (0.14-0.66) | 0.26 (0.11-0.57) | .45 |
| D-dimer, μg/mL | 2584 | 0.55 (0.35-0.86) | 0.38 (0.25-0.60) | <.0001 |
| WBC, ×103/μL | 2527 | 5.2 (4.2-6.3) | 5.3 (4.4-6.6) | .29 |
| Platelet count, ×103/μL | 2808 | 243 (208-288) | 245 (207-289) | .19 |
| P-selectin, ng/mL | 2055 | 31.9 (25.9-39.7) | 32.5 (26.0-40.3) | .92 |
| E-selectin, ng/mL | 2065 | 40.8 (27.8-55.9) | 41.3 (29.7-55.6) | .30 |