Characteristics of patients with HIT in pre-intervention and avoid-heparin phases
| Characteristic . | Pre-intervention phase, 2003-2005 (n = 53) No. (%)* . | Avoid-heparin phase, 2007-2012 (n = 26) No. (%)* . | P . |
|---|---|---|---|
| Median age, years (IQR) | 68 (60-74) | 72 (61-78) | .280 |
| Female | 30 (57) | 10 (38) | .130 |
| Primary admitting service | .950 | ||
| Cardiovascular surgery | 32 (60) | 15 (58) | |
| Other surgical service | 13 (24) | 6 (23) | |
| Cardiology | 4 (8) | 2 (8) | |
| Medicine | 4 (8) | 3 (11) | |
| Median duration of UFH or LMWH exposure before the diagnosis of HIT, days (IQR) | 10 (8-12) | 11 (8-13) | .526 |
| Median HIT ELISA OD (IQR) | 2.07 (1.21-2.40) | 2.79 (1.76-2.89) | .001 |
| HIT ELISA OD | .123 | ||
| <1.0 | 11 | 3 | |
| 1.0-2.0 | 15 | 5 | |
| >2.0 | 27 | 18 | |
| Median total length of stay, days (IQR)† | 24 (17-42) | 21 (14-28) | .224 |
| Median length of stay after HIT suspected, days (IQR)‡ | 14 (7-26) | 9 (6-20) | .198 |
| Characteristic . | Pre-intervention phase, 2003-2005 (n = 53) No. (%)* . | Avoid-heparin phase, 2007-2012 (n = 26) No. (%)* . | P . |
|---|---|---|---|
| Median age, years (IQR) | 68 (60-74) | 72 (61-78) | .280 |
| Female | 30 (57) | 10 (38) | .130 |
| Primary admitting service | .950 | ||
| Cardiovascular surgery | 32 (60) | 15 (58) | |
| Other surgical service | 13 (24) | 6 (23) | |
| Cardiology | 4 (8) | 2 (8) | |
| Medicine | 4 (8) | 3 (11) | |
| Median duration of UFH or LMWH exposure before the diagnosis of HIT, days (IQR) | 10 (8-12) | 11 (8-13) | .526 |
| Median HIT ELISA OD (IQR) | 2.07 (1.21-2.40) | 2.79 (1.76-2.89) | .001 |
| HIT ELISA OD | .123 | ||
| <1.0 | 11 | 3 | |
| 1.0-2.0 | 15 | 5 | |
| >2.0 | 27 | 18 | |
| Median total length of stay, days (IQR)† | 24 (17-42) | 21 (14-28) | .224 |
| Median length of stay after HIT suspected, days (IQR)‡ | 14 (7-26) | 9 (6-20) | .198 |