Table 1

Summary of achievement of tolerance to kidney transplants combined with HCT

Number of patients off IS drugs at last observation (N = 41)Medical centerHLA-matched or mismatchedDuration off IS drugs at last observation range (median) moChimerism status (# of patients)Reference
3* MGH Matched 3-85 (62) Transient mixed (3) 35 
17 SU Matched 2-66 (29) Transient mixed (10) 38-41 
Stable mixed (7) 
NW Matched 15-32 (20) Transient mixed (344 
No chimerism (2) 
MGH Mismatched 45-127 (51) Transient mixed (4) 45-47 
12 NW Mismatched 8-48 (29) Stable complete (11) 51-54 
Stable mixed (1) 
Number of patients off IS drugs at last observation (N = 41)Medical centerHLA-matched or mismatchedDuration off IS drugs at last observation range (median) moChimerism status (# of patients)Reference
3* MGH Matched 3-85 (62) Transient mixed (3) 35 
17 SU Matched 2-66 (29) Transient mixed (10) 38-41 
Stable mixed (7) 
NW Matched 15-32 (20) Transient mixed (344 
No chimerism (2) 
MGH Mismatched 45-127 (51) Transient mixed (4) 45-47 
12 NW Mismatched 8-48 (29) Stable complete (11) 51-54 
Stable mixed (1) 
*

Patients all had myeloma.

Chimerism <3% peak in blood.

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