Comparisons of Q fever patients according to lymphoma or benign lymphadenitis diagnoses
| . | n (%) or Mean ± SD . | P . | |||
|---|---|---|---|---|---|
| All, N = 1468 . | Lymphoma, n = 7 . | Lymphadenitis, n = 59 . | Q fever without lymphoma nor lymphadenitis, n = 1402 . | ||
| Age, y | 50.5 ± 17.1 | 62.7 ± 12.0 | 50.0 ± 20.1 | 50.4 ± 16.9 | .16* |
| Male sex | 998 (68) | 5 (71) | 50 (85)† | 943 (67)‡ | .018§ |
| Immunodepression | 159 (11) | 0 (0) | 10 (17) | 149 (11) | .20§ |
| History of valvulopathy | 361 (25) | 4 (57) | 13 (22) | 344 (25) | .12§ |
| Form of C burnetii infection | |||||
| Acute Q fever | 1096 (75) | 2 (29) | 41 (70) | 1053 (75) | .012§ |
| Acute Q fever without known progression to persistent focalized infection | 1028 (70) | 1 (14)† | 34 (58) | 993 (71)‖ | .001§ |
| Acute Q fever with progression to persistent focalized infection | 68 (5) | 1 (14) | 7 (12)† | 60 (4)‡ | .012§ |
| Persistent focalized infection | 440 (30) | 6 (86)† | 25 (42) | 409 (29)‖ | .001§ |
| Endocarditis | 331 (23) | 4 (57) | 11 (19) | 316 (22) | .07§ |
| Vascular infection | 68 (5) | 1 (14) | 2 (3) | 65 (5) | .43§ |
| Osteoarticular infections | 24 (1.6) | 0 (0) | 4 (7)† | 20 (1.5)‡ | .006§ |
| Pericarditis | 8 (0.5) | 0 (0) | 0 (0) | 8 (0.6) | .82§ |
| Pregnancy | 13 (1) | 0 (0) | 0 (0) | 13 (1) | .73§ |
| Isolated lymphadenitis | 10 (0.7) | 1 (14) | 9 (15) | — | — |
| Localization of lymphadenopathies | |||||
| Mediastinal | 31 (2) | 5 (71) | 26 (44) | — | .33¶ |
| Cervical | 15 (1) | 1 (14) | 14 (24) | — | .99¶ |
| Axillar | 10 (1) | 1 (14) | 9 (15) | — | .99¶ |
| Abdominal | 20 (1) | 4 (57) | 16 (27) | — | .23¶ |
| Inguinal | 7 (0.5) | 1 (14) | 6 (10) | — | .99¶ |
| . | n (%) or Mean ± SD . | P . | |||
|---|---|---|---|---|---|
| All, N = 1468 . | Lymphoma, n = 7 . | Lymphadenitis, n = 59 . | Q fever without lymphoma nor lymphadenitis, n = 1402 . | ||
| Age, y | 50.5 ± 17.1 | 62.7 ± 12.0 | 50.0 ± 20.1 | 50.4 ± 16.9 | .16* |
| Male sex | 998 (68) | 5 (71) | 50 (85)† | 943 (67)‡ | .018§ |
| Immunodepression | 159 (11) | 0 (0) | 10 (17) | 149 (11) | .20§ |
| History of valvulopathy | 361 (25) | 4 (57) | 13 (22) | 344 (25) | .12§ |
| Form of C burnetii infection | |||||
| Acute Q fever | 1096 (75) | 2 (29) | 41 (70) | 1053 (75) | .012§ |
| Acute Q fever without known progression to persistent focalized infection | 1028 (70) | 1 (14)† | 34 (58) | 993 (71)‖ | .001§ |
| Acute Q fever with progression to persistent focalized infection | 68 (5) | 1 (14) | 7 (12)† | 60 (4)‡ | .012§ |
| Persistent focalized infection | 440 (30) | 6 (86)† | 25 (42) | 409 (29)‖ | .001§ |
| Endocarditis | 331 (23) | 4 (57) | 11 (19) | 316 (22) | .07§ |
| Vascular infection | 68 (5) | 1 (14) | 2 (3) | 65 (5) | .43§ |
| Osteoarticular infections | 24 (1.6) | 0 (0) | 4 (7)† | 20 (1.5)‡ | .006§ |
| Pericarditis | 8 (0.5) | 0 (0) | 0 (0) | 8 (0.6) | .82§ |
| Pregnancy | 13 (1) | 0 (0) | 0 (0) | 13 (1) | .73§ |
| Isolated lymphadenitis | 10 (0.7) | 1 (14) | 9 (15) | — | — |
| Localization of lymphadenopathies | |||||
| Mediastinal | 31 (2) | 5 (71) | 26 (44) | — | .33¶ |
| Cervical | 15 (1) | 1 (14) | 14 (24) | — | .99¶ |
| Axillar | 10 (1) | 1 (14) | 9 (15) | — | .99¶ |
| Abdominal | 20 (1) | 4 (57) | 16 (27) | — | .23¶ |
| Inguinal | 7 (0.5) | 1 (14) | 6 (10) | — | .99¶ |
—, not applicable.
One-way analysis of variance test with the Tukey multiple comparison test.
Cells with a significant difference compared with “Q fever without lymphoma nor lymphadenitis” column (z-test comparing column proportion with the Dunn test for multiple comparisons).
Cells with a significant difference compared with “Lymphadenitis” column (z-test comparing column proportion with the Dunn test for multiple comparisons).
χ2 test for 3 groups.
Cells with a significant difference compared with “Lymphoma” column (z-test comparing column proportion with the Dunn test for multiple comparisons).
Fisher exact test.