Multivariate analysis (Cox proportional hazard models for either OS or PFS)
| Parameter . | HR . | 95% CI . | P . |
|---|---|---|---|
| Multivariate analysis of OS (103 subjects, 6 deaths) | |||
| MTV (increments of 102 ml) | 0.96 | 0.66-1.40 | .833 |
| TLG (increments of 103) | 1.49 | 1.18-1.89 | .001 |
| Multivariate analysis of PFS (103 subjects, 13 events) | |||
| Bulky disease (<10 cm vs ≥10 cm) | 1.73 | 0.31-9.52 | .526 |
| MTV (increments of 102 mL) | 1.03 | 0.80-1.33 | .812 |
| TLG (increments of 103 mL) | 1.36 | 1.16-1.58 | <.001 |
| Parameter . | HR . | 95% CI . | P . |
|---|---|---|---|
| Multivariate analysis of OS (103 subjects, 6 deaths) | |||
| MTV (increments of 102 ml) | 0.96 | 0.66-1.40 | .833 |
| TLG (increments of 103) | 1.49 | 1.18-1.89 | .001 |
| Multivariate analysis of PFS (103 subjects, 13 events) | |||
| Bulky disease (<10 cm vs ≥10 cm) | 1.73 | 0.31-9.52 | .526 |
| MTV (increments of 102 mL) | 1.03 | 0.80-1.33 | .812 |
| TLG (increments of 103 mL) | 1.36 | 1.16-1.58 | <.001 |
Each as a whole was statistically significant, and in both models, TLG resulted in a significantly longer survival time after controlling for mediastinal bulk and MTV in PFS and for MTV in OS.