Prognostic scoring systems for patients with refractory/relapsed AML: European Prognostic Index score
Factor . | Points . |
---|---|
CR1 duration | |
≥18 mo | 0 |
7-18 mo | 3 |
≤6 months | 5 |
Cytogenetics at diagnosis | |
t(16;16) or inv16 | 0 |
t(8;21) | 3 |
Other | 5 |
Age at relapse | |
≤35 y | 0 |
36-45 y | 1 |
>45 y | 2 |
SCT before first relapse | |
No | 0 |
Yes | 2 |
Factor . | Points . |
---|---|
CR1 duration | |
≥18 mo | 0 |
7-18 mo | 3 |
≤6 months | 5 |
Cytogenetics at diagnosis | |
t(16;16) or inv16 | 0 |
t(8;21) | 3 |
Other | 5 |
Age at relapse | |
≤35 y | 0 |
36-45 y | 1 |
>45 y | 2 |
SCT before first relapse | |
No | 0 |
Yes | 2 |
For information on the EPI score, see Breems et al.34 Prognostic groups: favorable (1-6 points; OS of 70% at 1 y and 46% at 5 y); intermediate (7-9 points; OS of 49% at 1 y and 18% at 5 y); poor (10-14 points; OS of 16% at 1 y and 4% at 5 y).
SCT, stem cell transplantation.