Table 2

Prognostic scoring systems for patients with refractory/relapsed AML: European Prognostic Index score

FactorPoints
CR1 duration  
 ≥18 mo 
 7-18 mo 
 ≤6 months 
Cytogenetics at diagnosis  
 t(16;16) or inv16 
 t(8;21) 
 Other 
Age at relapse  
 ≤35 y 
 36-45 y 
 >45 y 
SCT before first relapse  
 No 
 Yes 
FactorPoints
CR1 duration  
 ≥18 mo 
 7-18 mo 
 ≤6 months 
Cytogenetics at diagnosis  
 t(16;16) or inv16 
 t(8;21) 
 Other 
Age at relapse  
 ≤35 y 
 36-45 y 
 >45 y 
SCT before first relapse  
 No 
 Yes 

For information on the EPI score, see Breems et al.34  Prognostic groups: favorable (1-6 points; OS of 70% at 1 y and 46% at 5 y); intermediate (7-9 points; OS of 49% at 1 y and 18% at 5 y); poor (10-14 points; OS of 16% at 1 y and 4% at 5 y).

SCT, stem cell transplantation.

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