Platelet surface glycoprotein expression in whole blood of Vps33bfl/fl-ERT2 mice
| Surface glycoproteins . | Vps33bfl/fl (Mean ± SEM; n = 8) . | Vps33bfl/fl-ERT2 (Mean ± SEM; n = 6) . |
|---|---|---|
| GPVI | 15.5 ± 0.7 | 12.3 ± 0.7** |
| Integrin α2 | 12.3 ± 0.7 | 11.7 ± 1.1 |
| Integrin αIIbβ3 | 140.2 ± 9.9 | 108.9 ± 13.2 |
| GP1bα | 32.1 ± 2.2 | 35.8 ± 2.9 |
| αIIbβ3 activity | 68.7 ± 5.9 | 57.8 ± 5.6 |
| Surface glycoproteins . | Vps33bfl/fl (Mean ± SEM; n = 8) . | Vps33bfl/fl-ERT2 (Mean ± SEM; n = 6) . |
|---|---|---|
| GPVI | 15.5 ± 0.7 | 12.3 ± 0.7** |
| Integrin α2 | 12.3 ± 0.7 | 11.7 ± 1.1 |
| Integrin αIIbβ3 | 140.2 ± 9.9 | 108.9 ± 13.2 |
| GP1bα | 32.1 ± 2.2 | 35.8 ± 2.9 |
| αIIbβ3 activity | 68.7 ± 5.9 | 57.8 ± 5.6 |
αIIbβ3 activity: fibrinogen binging to αIIbβ3 in response to 0.1 U/mL thrombin.
P < .01.