Grades 3 and 4 toxicities reported during R-MPV (N = 32)
| Toxicity . | Grade 3 . | Grade 4 . | ||
|---|---|---|---|---|
| Hemoglobin | 6 | 18% | ||
| Neutrophils | 6 | 18% | 1 | 3% |
| ALT and/or AST | 14 | 42% | 3 | 9% |
| Creatinine | 5 | 15% | ||
| Infection | 4 | 12% | ||
| Peripheral neuropathy | 2 | 6% | ||
| Fatigue | 2 | 6% | ||
| Thrombosis/embolism | 1 | 3% | 2 | 6% |
| Constipation | 1 | 3% | ||
| Syncope | 1 | 3% | ||
| Encephalopathy | 1 | 3% | ||
| Toxicity . | Grade 3 . | Grade 4 . | ||
|---|---|---|---|---|
| Hemoglobin | 6 | 18% | ||
| Neutrophils | 6 | 18% | 1 | 3% |
| ALT and/or AST | 14 | 42% | 3 | 9% |
| Creatinine | 5 | 15% | ||
| Infection | 4 | 12% | ||
| Peripheral neuropathy | 2 | 6% | ||
| Fatigue | 2 | 6% | ||
| Thrombosis/embolism | 1 | 3% | 2 | 6% |
| Constipation | 1 | 3% | ||
| Syncope | 1 | 3% | ||
| Encephalopathy | 1 | 3% | ||
ALT, alanine aminotransferase; AST, aspartate aminotransferase.