Correlations of tmTNF-α expression with clinical features of ALL
| Characteristics . | Cases . | Expression (%) of tmTNF-α (mean ± SEM) . | P . |
|---|---|---|---|
| Subtype | .9987 | ||
| B-ALL | 15 | 65.06 ± 9.351 | |
| T-ALL | 16 | 69.08 ± 9.975 | |
| Age (y) | .2976 | ||
| >35 | 12 | 55.23 ± 12.57 | |
| ≤35 | 18 | 70.16 ± 7.89 | |
| BM blasts | .9393 | ||
| >Median | 15 | 63.35 ± 10.12 | |
| ≤Median | 15 | 62.27 ± 9.741 | |
| White cell count (×10−3/mm3) | <.05 | ||
| >30 | 14 | 81.31 ± 7.578 | |
| ≤30 | 17 | 51.69 ± 9.597 | |
| Risk status*(cytogenetic abnormalities) | .5525 | ||
| Adverse | 10 | 55.8 ± 18.56 | |
| Others | 20 | 72.7 ± 23.32 | |
| Risk status*(exclude Ph+) | <.01 | ||
| Standard risk | 16 | 51.74 ± 10.07 | |
| Poor risk | 10 | 91.04 ± 3.306 | |
| Risk status* | .5958 | ||
| Ph+ | 5 | 55.8 ± 18.56 | |
| Ph− | 25 | 65.87 ± 7.551 | |
| Extramedullary infiltration | <.01 | ||
| Yes | 24 | 74.57 ± 6.748 | |
| No | 7 | 32.51 ± 13.38 |
| Characteristics . | Cases . | Expression (%) of tmTNF-α (mean ± SEM) . | P . |
|---|---|---|---|
| Subtype | .9987 | ||
| B-ALL | 15 | 65.06 ± 9.351 | |
| T-ALL | 16 | 69.08 ± 9.975 | |
| Age (y) | .2976 | ||
| >35 | 12 | 55.23 ± 12.57 | |
| ≤35 | 18 | 70.16 ± 7.89 | |
| BM blasts | .9393 | ||
| >Median | 15 | 63.35 ± 10.12 | |
| ≤Median | 15 | 62.27 ± 9.741 | |
| White cell count (×10−3/mm3) | <.05 | ||
| >30 | 14 | 81.31 ± 7.578 | |
| ≤30 | 17 | 51.69 ± 9.597 | |
| Risk status*(cytogenetic abnormalities) | .5525 | ||
| Adverse | 10 | 55.8 ± 18.56 | |
| Others | 20 | 72.7 ± 23.32 | |
| Risk status*(exclude Ph+) | <.01 | ||
| Standard risk | 16 | 51.74 ± 10.07 | |
| Poor risk | 10 | 91.04 ± 3.306 | |
| Risk status* | .5958 | ||
| Ph+ | 5 | 55.8 ± 18.56 | |
| Ph− | 25 | 65.87 ± 7.551 | |
| Extramedullary infiltration | <.01 | ||
| Yes | 24 | 74.57 ± 6.748 | |
| No | 7 | 32.51 ± 13.38 |
Differences between 2 groups were analyzed by the Student t test.
Risk status stratification is according to NCCN guidelines (2012).