Table 2 Detected pathogens in BAL... | American Society of Hematology

Table 2

Detected pathogens in BAL samples at diagnosis

Pathogenicity in lung	Detected pathogens	IPS cases (N = 69)		Controls (N = 21)		P†
		Pathogen load		Pathogen load
		Any (N = 39)	High* (N = 12)	Any (N = 13)	High* (N = 1)
Established	Aspergillus‡	8 (12)	N/A	3 (14)	N/A	.71
	CMV	8 (12)	0 (0)	6 (29)	0 (0)	.08
	PIV	2 (3)	0 (0)	0 (0)	0 (0)	1.00
	RSV	2 (3)	1 (1)	0 (0)	0 (0)	1.00
	HMPV	2 (3)	2 (3)	0 (0)	0 (0)	1.00
Uncertain	HHV-6	20 (29)	4 (6)	1 (5)	0 (0)	.020
	HRV	8 (12)	6 (9)	1 (5)	0 (0)	.68
	KIPyV	3 (4)	1 (1)	5 (24)	0 (0)	.016
	BKV	3 (4)	0 (0)	0 (0)	0 (0)	1.00
	HSV	2 (3)	0 (0)	0 (0)	0 (0)	1.00
	EBV	1 (1)	0 (0)	2 (10)	0 (0)	.14
	WUPyV	1 (1)	0 (0)	0 (0)	0 (0)	1.00
	CoV	0 (0)	0 (0)	1 (5)	1 (5)	.23

Pathogenicity in lung	Detected pathogens	IPS cases (N = 69)		Controls (N = 21)		P†
		Pathogen load		Pathogen load
		Any (N = 39)	High* (N = 12)	Any (N = 13)	High* (N = 1)
Established	Aspergillus‡	8 (12)	N/A	3 (14)	N/A	.71
	CMV	8 (12)	0 (0)	6 (29)	0 (0)	.08
	PIV	2 (3)	0 (0)	0 (0)	0 (0)	1.00
	RSV	2 (3)	1 (1)	0 (0)	0 (0)	1.00
	HMPV	2 (3)	2 (3)	0 (0)	0 (0)	1.00
Uncertain	HHV-6	20 (29)	4 (6)	1 (5)	0 (0)	.020
	HRV	8 (12)	6 (9)	1 (5)	0 (0)	.68
	KIPyV	3 (4)	1 (1)	5 (24)	0 (0)	.016
	BKV	3 (4)	0 (0)	0 (0)	0 (0)	1.00
	HSV	2 (3)	0 (0)	0 (0)	0 (0)	1.00
	EBV	1 (1)	0 (0)	2 (10)	0 (0)	.14
	WUPyV	1 (1)	0 (0)	0 (0)	0 (0)	1.00
	CoV	0 (0)	0 (0)	1 (5)	1 (5)	.23

All values are indicated as the number of cases (percentage of cases with pathogens).

N/A, not applicable.

High load: >10⁵ copies per mL, <32 cycle threshold (for HRV).

The values were obtained from the comparison in the number of patients with any pathogens between IPS cases and controls.

The median values of galactomannan were 0.65 (range, 0.57-2.37) in IPS cases and 1.46 (range, 0.62-2.24) in controls.