Most common sites of involvement in PBL (literature review from 1997 to 2014)
| Sites of involvement . | Total Cases . | HIV-positive . | HIV-negative . | Posttransplant . | Transformed . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | |
| Oral | 260 | 44 | 178 | 48 | 65 | 40 | 6 | 16 | 11 | 55 |
| Gastrointestinal | 83 | 14 | 43 | 12 | 34 | 21 | 3 | 8 | 3 | 15 |
| Lymph nodes | 43 | 7 | 17 | 5 | 14 | 9 | 11 | 30 | 1 | 5 |
| Skin | 41 | 7 | 22 | 6 | 10 | 7 | 8 | 22 | 1 | 5 |
| Bone | 26 | 4 | 19 | 5 | 4 | 2 | 2 | 5 | 1 | 5 |
| Genitourinary | 23 | 4 | 12 | 3 | 6 | 4 | 2 | 5 | 3 | 15 |
| Nose | 18 | 3 | 11 | 3 | 6 | 4 | 1 | 3 | — | |
| Central nervous system | 17 | 3 | 12 | 3 | 4 | 2 | 1 | 3 | — | |
| Liver | 11 | 2 | 8 | 2 | 2 | 1 | 1 | 3 | — | |
| Lung | 11 | 2 | 9 | 2 | 1 | 0.6 | 1 | 3 | — | |
| Orbit | 10 | 2 | 8 | 2 | 2 | 1 | — | — | ||
| Spleen | 5 | 0.8 | 4 | 1 | 1 | 0.6 | — | — | ||
| Skull | 5 | 0.8 | 4 | 1 | 1 | 0.6 | — | — | ||
| Retroperitoneum | 4 | 0.7 | 1 | 0.2 | 3 | 2 | — | — | ||
| Breast | 3 | 0.5 | 1 | 0.2 | 1 | 0.6 | 1 | 3 | — | |
| Larynx | 2 | 0.3 | 2 | 0.5 | — | — | — | |||
| Gallbladder | 2 | 0.3 | 2 | 0.5 | — | — | — | |||
| Choroid | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Heart | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Parotid | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Muscle | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Not specified | 22 | 4 | 16 | 4 | 6 | 4 | — | — | ||
| Total | 590 | 369 | 164 | 37 | 20 | |||||
| Sites of involvement . | Total Cases . | HIV-positive . | HIV-negative . | Posttransplant . | Transformed . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | |
| Oral | 260 | 44 | 178 | 48 | 65 | 40 | 6 | 16 | 11 | 55 |
| Gastrointestinal | 83 | 14 | 43 | 12 | 34 | 21 | 3 | 8 | 3 | 15 |
| Lymph nodes | 43 | 7 | 17 | 5 | 14 | 9 | 11 | 30 | 1 | 5 |
| Skin | 41 | 7 | 22 | 6 | 10 | 7 | 8 | 22 | 1 | 5 |
| Bone | 26 | 4 | 19 | 5 | 4 | 2 | 2 | 5 | 1 | 5 |
| Genitourinary | 23 | 4 | 12 | 3 | 6 | 4 | 2 | 5 | 3 | 15 |
| Nose | 18 | 3 | 11 | 3 | 6 | 4 | 1 | 3 | — | |
| Central nervous system | 17 | 3 | 12 | 3 | 4 | 2 | 1 | 3 | — | |
| Liver | 11 | 2 | 8 | 2 | 2 | 1 | 1 | 3 | — | |
| Lung | 11 | 2 | 9 | 2 | 1 | 0.6 | 1 | 3 | — | |
| Orbit | 10 | 2 | 8 | 2 | 2 | 1 | — | — | ||
| Spleen | 5 | 0.8 | 4 | 1 | 1 | 0.6 | — | — | ||
| Skull | 5 | 0.8 | 4 | 1 | 1 | 0.6 | — | — | ||
| Retroperitoneum | 4 | 0.7 | 1 | 0.2 | 3 | 2 | — | — | ||
| Breast | 3 | 0.5 | 1 | 0.2 | 1 | 0.6 | 1 | 3 | — | |
| Larynx | 2 | 0.3 | 2 | 0.5 | — | — | — | |||
| Gallbladder | 2 | 0.3 | 2 | 0.5 | — | — | — | |||
| Choroid | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Heart | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Parotid | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Muscle | 1 | 0.1 | — | 1 | 0.6 | — | — | |||
| Not specified | 22 | 4 | 16 | 4 | 6 | 4 | — | — | ||
| Total | 590 | 369 | 164 | 37 | 20 | |||||