VWF laboratory values for healthy controls and type 1 VWD subjects
| . | Healthy controls (n = 246) . | Type 1 VWD subjects (n = 299) . | ||||
|---|---|---|---|---|---|---|
| . | Mean . | Median . | IQR . | Mean . | Median . | IQR . |
| VWF:Ag | 127 | 111 | 88-150 | 33 | 36 | 22-46 |
| VWF:RCo | 122 | 114 | 82-148 | 32 | 35 | 20-44 |
| VWF:RCo/VWF:Ag ratio | 0.98 | 0.97 | 0.86-1.10 | 1.00 | 0.97 | 0.84-1.12 |
| VWF:CB3 | 132 | 120 | 94-161 | 37 | 41 | 22-52 |
| VWF:CB3/VWF:Ag ratio | 1.06 | 1.06 | 0.96-1.17 | 1.12 | 1.13 | 1.02-1.25 |
| VWF:CB4 | 123 | 107 | 75-153 | 29 | 30 | 16-42 |
| VWF:CB4/VWF:Ag ratio | 0.96 | 0.94 | 0.78-1.09 | 0.86 | 0.88 | 0.74-0.98 |
| . | Healthy controls (n = 246) . | Type 1 VWD subjects (n = 299) . | ||||
|---|---|---|---|---|---|---|
| . | Mean . | Median . | IQR . | Mean . | Median . | IQR . |
| VWF:Ag | 127 | 111 | 88-150 | 33 | 36 | 22-46 |
| VWF:RCo | 122 | 114 | 82-148 | 32 | 35 | 20-44 |
| VWF:RCo/VWF:Ag ratio | 0.98 | 0.97 | 0.86-1.10 | 1.00 | 0.97 | 0.84-1.12 |
| VWF:CB3 | 132 | 120 | 94-161 | 37 | 41 | 22-52 |
| VWF:CB3/VWF:Ag ratio | 1.06 | 1.06 | 0.96-1.17 | 1.12 | 1.13 | 1.02-1.25 |
| VWF:CB4 | 123 | 107 | 75-153 | 29 | 30 | 16-42 |
| VWF:CB4/VWF:Ag ratio | 0.96 | 0.94 | 0.78-1.09 | 0.86 | 0.88 | 0.74-0.98 |
IQR, interquartile range (25th-75th).
Data are given in IU/dL with the exception of VWF:CB4, which was normalized to an international standard and is given in U/dL. For subjects with values below the lower limit of detection for each assay, an arbitrary value was assigned for calculation purposes (5 IU/dL for VWF:RCo <10 IU/dL, 0.5 IU/dL for VWF:CB3 <1 IU/dL, and 0.8 U/dL for VWF:CB4 <1.6 U/dL).