Associated risk factors for isolated eICA of 160 cm/s or more and eICA stenosis (logistic regression analysis)
| Concomitant parameters . | Associated risk factors . | |||
|---|---|---|---|---|
| Isolated eICA ≥160 cm/sec . | Isolated eICA stenosis . | |||
| OR (95% CI) . | P . | OR (95% CI) . | P . | |
| Univariate logistic regression analysis | ||||
| Tortuosities | 27.8 (9.1-83.3) | <.001* | 29.41 (6.45-125) | <.001* |
| Age per 1 y increase | 1.13 (1.02-1.25) | .015* | 1.05 (0.95-1.16) | .363 |
| Leukocyte count per 1 × 109/L increase | 1.14 (1.02-1.28) | .017* | 1.17 (1.04-1.32) | .010* |
| Neutrophil count per 1 × 109/L increase | 1.16 (0.99-1.36) | .051 | 1.17 (1.04-1.32) | .07 |
| Platelet count per 1 × 109/L increase | 1.001 (0.996-1.003) | .903 | 1.000 (0.996-1.004) | .895 |
| Hemoglobin level per 1 g/dL decrease | 2.19 (1.30-3.69) | .003* | 1.38 (0.87-2.19) | .169 |
| Mean corpuscular volume per fL increase | 1.03 (0.97-1.08) | .346 | 1.005 (0.947-1.067) | .868 |
| Reticulocyte count per 1 × 109/L increase | 1.003 (0.998-1.007) | .211 | 1.005 (1.000-1.010) | .051 |
| HbF per 1% increase | 1.02 (0.95-1.09) | .648 | 1.02 (0.94-1.10) | .649 |
| SpO2 per 1% increase | 1.29 (0.99-1.69) | .063 | 1.07 (0.77-1.48) | .696 |
| LDH per IU/mL increase | 30.02 (1.02-885.71) | .049* | 68.9 (1.52-3128) | .030* |
| HbS% per 1% increase | 1.030 (1.003-1.057) | .026* | 1.001 (0.979-1.023) | .962 |
| Absence of intensive therapy (HU or TP) | 5.01 (2.03-12.36) | <.001* | 2.67 (1.02-6.95) | .045* |
| Isolated eICA ≥160 cm/s | 14.49 (5.24-40) | <.001* | ||
| Multivariate analysis | ||||
| Tortuosities | 23.26 (5.95-90.91) | <.001* | 10.31 (2.51-41.67) | .001* |
| Hemoglobin level per 1 g/dL decrease | 2.20 (1.22-3.97) | .009* | ||
| Isolated eICA ≥160 cm/s | 4.39 (1.39-13.9) | .012* | ||
| Concomitant parameters . | Associated risk factors . | |||
|---|---|---|---|---|
| Isolated eICA ≥160 cm/sec . | Isolated eICA stenosis . | |||
| OR (95% CI) . | P . | OR (95% CI) . | P . | |
| Univariate logistic regression analysis | ||||
| Tortuosities | 27.8 (9.1-83.3) | <.001* | 29.41 (6.45-125) | <.001* |
| Age per 1 y increase | 1.13 (1.02-1.25) | .015* | 1.05 (0.95-1.16) | .363 |
| Leukocyte count per 1 × 109/L increase | 1.14 (1.02-1.28) | .017* | 1.17 (1.04-1.32) | .010* |
| Neutrophil count per 1 × 109/L increase | 1.16 (0.99-1.36) | .051 | 1.17 (1.04-1.32) | .07 |
| Platelet count per 1 × 109/L increase | 1.001 (0.996-1.003) | .903 | 1.000 (0.996-1.004) | .895 |
| Hemoglobin level per 1 g/dL decrease | 2.19 (1.30-3.69) | .003* | 1.38 (0.87-2.19) | .169 |
| Mean corpuscular volume per fL increase | 1.03 (0.97-1.08) | .346 | 1.005 (0.947-1.067) | .868 |
| Reticulocyte count per 1 × 109/L increase | 1.003 (0.998-1.007) | .211 | 1.005 (1.000-1.010) | .051 |
| HbF per 1% increase | 1.02 (0.95-1.09) | .648 | 1.02 (0.94-1.10) | .649 |
| SpO2 per 1% increase | 1.29 (0.99-1.69) | .063 | 1.07 (0.77-1.48) | .696 |
| LDH per IU/mL increase | 30.02 (1.02-885.71) | .049* | 68.9 (1.52-3128) | .030* |
| HbS% per 1% increase | 1.030 (1.003-1.057) | .026* | 1.001 (0.979-1.023) | .962 |
| Absence of intensive therapy (HU or TP) | 5.01 (2.03-12.36) | <.001* | 2.67 (1.02-6.95) | .045* |
| Isolated eICA ≥160 cm/s | 14.49 (5.24-40) | <.001* | ||
| Multivariate analysis | ||||
| Tortuosities | 23.26 (5.95-90.91) | <.001* | 10.31 (2.51-41.67) | .001* |
| Hemoglobin level per 1 g/dL decrease | 2.20 (1.22-3.97) | .009* | ||
| Isolated eICA ≥160 cm/s | 4.39 (1.39-13.9) | .012* | ||
Significant tests.