Summary of peripheral blood hematologic parameters for wild-type and Cc2−/− mice
| Hematologic parameter . | Wild-type (n = 6) . | Cc2−/− (n = 6) . |
|---|---|---|
| WBC, ×109/L | 6.20 ± 1.03 | 5.25 ± 0.66 |
| RBC, ×1012/L | 9.07 ± 0.22 | 8.89 ± 0.46 |
| HGB, g/L | 132.33 ± 3.08 | 129.33 ± 6.90 |
| PCV, L/L | 0.43 ± 0.01 | 0.42 ± 0.02 |
| MCV, fl | 48.33 ± 0.55 | 48.00 ± 0.85 |
| MCH, pg | 14.61 ± 0.24 | 14.56 ± 0.23 |
| MCHC, ×103 g/L | 302.00 ± 3.40 | 303.83 ± 3.21 |
| RDW, % | 13.25 ± 0.18 | 13.58 ± 0.19 |
| PLT, ×109/L | 726.66 ± 23.10 | 741.00 ± 9.80 |
| WBC/Neut/, % | 8.58 ± 1.72 | 7.41 ± 1.50 |
| WBC/Lymph, % | 88.91 ± 2.34 | 90.00 ± 2.27 |
| WBC/Mono, % | 2.50 ± 0.65 | 3.08 ± 1.26 |
| WBC/Neut, ×109/L | 0.55 ± 0.17 | 0.37 ± 0.07 |
| WBC/Lymph, ×109/L | 5.47 ± 0.88 | 4.74 ± 0.65 |
| WBC/Mono, ×109/L | 0.17 ± 0.06 | 0.16 ± 0.07 |
| Hematologic parameter . | Wild-type (n = 6) . | Cc2−/− (n = 6) . |
|---|---|---|
| WBC, ×109/L | 6.20 ± 1.03 | 5.25 ± 0.66 |
| RBC, ×1012/L | 9.07 ± 0.22 | 8.89 ± 0.46 |
| HGB, g/L | 132.33 ± 3.08 | 129.33 ± 6.90 |
| PCV, L/L | 0.43 ± 0.01 | 0.42 ± 0.02 |
| MCV, fl | 48.33 ± 0.55 | 48.00 ± 0.85 |
| MCH, pg | 14.61 ± 0.24 | 14.56 ± 0.23 |
| MCHC, ×103 g/L | 302.00 ± 3.40 | 303.83 ± 3.21 |
| RDW, % | 13.25 ± 0.18 | 13.58 ± 0.19 |
| PLT, ×109/L | 726.66 ± 23.10 | 741.00 ± 9.80 |
| WBC/Neut/, % | 8.58 ± 1.72 | 7.41 ± 1.50 |
| WBC/Lymph, % | 88.91 ± 2.34 | 90.00 ± 2.27 |
| WBC/Mono, % | 2.50 ± 0.65 | 3.08 ± 1.26 |
| WBC/Neut, ×109/L | 0.55 ± 0.17 | 0.37 ± 0.07 |
| WBC/Lymph, ×109/L | 5.47 ± 0.88 | 4.74 ± 0.65 |
| WBC/Mono, ×109/L | 0.17 ± 0.06 | 0.16 ± 0.07 |
Hematologic parameters were analyzed from wild-type and Cc2−/− whole blood. Hgb, hemoglobin; PCV, packed cell volume; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; PLT, platelets; Neut, neutrophils; Lymph, lymphocytes; Mono, monocytes. The assays were run in triplicate, and the data shown are representative of 6 independent experiments and presented as MFI ± standard error of the mean (SEM) (P > .05 is nonsignificant for all hematologic parameters) using statistics Student t test.