Table 1

Monitoring the PNH patient on eculizumab

Monthly (draw tests before drug infusion)Yearly
Complete blood count PNH flow cytometry 
Reticulocyte count  
Serum bilirubin  
Serum LDH  
  
If evidence of extravascular hemolysis (anemia and elevated reticulocyte count) 
 Direct antiglobulin test  
Monthly (draw tests before drug infusion)Yearly
Complete blood count PNH flow cytometry 
Reticulocyte count  
Serum bilirubin  
Serum LDH  
  
If evidence of extravascular hemolysis (anemia and elevated reticulocyte count) 
 Direct antiglobulin test  

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