Age- and sex-specific cutoff levels for the different D-dimer assays adopted in the study
| Commercial D-dimer assay (manufacturer) ng/mL . | Males ≤70 y . | Males >70 y . | Females ≤70 y . | Females >70 y . | Cutoff values currently recommended by manufacturers for VTE exclusion . |
|---|---|---|---|---|---|
| VIDAS D-dimer Exclusion (bio-Merrieux) | 490 | 1050 | 600 | 1300 | 500 |
| Innovance D-DIMER (Siemens) | 500 | 950 | 550 | 1150 | 500 |
| HemosIL D-dimer HS (Instrumentation Laboratory) | 170 | 345 | 215 | 430 | 230 |
| HemosIL D-dimer (Instrumentation Laboratory) | 205 | 300 | 225 | 330 | 230 |
| STA Liatest D-dimer (Diagnostica Stago) | 340 | 700 | 450 | 1050 | 500 |
| Commercial D-dimer assay (manufacturer) ng/mL . | Males ≤70 y . | Males >70 y . | Females ≤70 y . | Females >70 y . | Cutoff values currently recommended by manufacturers for VTE exclusion . |
|---|---|---|---|---|---|
| VIDAS D-dimer Exclusion (bio-Merrieux) | 490 | 1050 | 600 | 1300 | 500 |
| Innovance D-DIMER (Siemens) | 500 | 950 | 550 | 1150 | 500 |
| HemosIL D-dimer HS (Instrumentation Laboratory) | 170 | 345 | 215 | 430 | 230 |
| HemosIL D-dimer (Instrumentation Laboratory) | 205 | 300 | 225 | 330 | 230 |
| STA Liatest D-dimer (Diagnostica Stago) | 340 | 700 | 450 | 1050 | 500 |
For comparison, the cutoff values recommended by manufacturers for VTE exclusion are also shown.