Clinical characteristics of PRKACG-related thrombocytopenia patients
| Family member . | Age at diagnosis (years) . | Current age (years) . | Platelet count (×109/L) . | MPV (fL) . | Hemoglobin (g/dL) . | Leukocytes (×109/L) . | Bleeding score . | TPO level (ng/L) . |
|---|---|---|---|---|---|---|---|---|
| I-1 | 44 | 210 | 10.3 | 11 | 4.5 | NB | 35 | |
| II-1 | 4 | 23 | 5 | ND | 9 | 5 | 3 | 23 |
| II-2 | 2 | 26 | 8 | ND | 12.3 | 5.6 | 2 | 25 |
| II-3 | 21 | 229 | 10.8 | 12.9 | 7.1 | NB | 20 | |
| III-1 | 3 | 276 | 10.4 | 10.4 | 8 | NB | 30 | |
| III-2 | 90 d | 277 | 11 | 17 | 14 | NB | ND |
| Family member . | Age at diagnosis (years) . | Current age (years) . | Platelet count (×109/L) . | MPV (fL) . | Hemoglobin (g/dL) . | Leukocytes (×109/L) . | Bleeding score . | TPO level (ng/L) . |
|---|---|---|---|---|---|---|---|---|
| I-1 | 44 | 210 | 10.3 | 11 | 4.5 | NB | 35 | |
| II-1 | 4 | 23 | 5 | ND | 9 | 5 | 3 | 23 |
| II-2 | 2 | 26 | 8 | ND | 12.3 | 5.6 | 2 | 25 |
| II-3 | 21 | 229 | 10.8 | 12.9 | 7.1 | NB | 20 | |
| III-1 | 3 | 276 | 10.4 | 10.4 | 8 | NB | 30 | |
| III-2 | 90 d | 277 | 11 | 17 | 14 | NB | ND |
Normal TPO level, <30 ng/L. MPV, mean platelet volume; NB, no bleeding; ND, not done.