LIC determination in non-t(4;11) pre-B ALL with TBI preconditioning based xenotransplantation
| UPN . | TBI dose (Gy) . | . | LIC frequency (95% confidence interval) . | |||
|---|---|---|---|---|---|---|
| Cells per injection | ||||||
| 20 | 2.5 | 1.8 × 106 | 1.8 × 105 | 1.8 × 104 | 1.8 × 103 | |
| No. of mice engrafting | <1/3900 (1/880-1/17 000) | |||||
| 3/3 | 2/2 | 3/3 | 1/3 | |||
| Cells per injection | ||||||
| 21 | 2.5 | 5.6 × 106 | — | — | 2.78 × 103 | |
| No. of mice engrafting | <1/6800 (1/960-1/49 000) | |||||
| 2/2 | ND | ND | 1/3 | |||
| Cells per injection | ||||||
| 21 | 2 | ND | 4.5 × 105 | 4.5 × 104 | 4.5 × 103 | |
| No. of mice engrafting | <1/20 000 (1/7000-1/59 000) | |||||
| ND | 4/4 | 4/4 | 0/5 | |||
| UPN . | TBI dose (Gy) . | . | LIC frequency (95% confidence interval) . | |||
|---|---|---|---|---|---|---|
| Cells per injection | ||||||
| 20 | 2.5 | 1.8 × 106 | 1.8 × 105 | 1.8 × 104 | 1.8 × 103 | |
| No. of mice engrafting | <1/3900 (1/880-1/17 000) | |||||
| 3/3 | 2/2 | 3/3 | 1/3 | |||
| Cells per injection | ||||||
| 21 | 2.5 | 5.6 × 106 | — | — | 2.78 × 103 | |
| No. of mice engrafting | <1/6800 (1/960-1/49 000) | |||||
| 2/2 | ND | ND | 1/3 | |||
| Cells per injection | ||||||
| 21 | 2 | ND | 4.5 × 105 | 4.5 × 104 | 4.5 × 103 | |
| No. of mice engrafting | <1/20 000 (1/7000-1/59 000) | |||||
| ND | 4/4 | 4/4 | 0/5 | |||
The number of mice engrafting over the total number injected is shown. LIC frequencies were calculated using the open access program ELDA (http://bioinf.wehi.edu.au/software/elda/). ND, not determined.